| Name | hCE 2 |
|---|---|
| Synonyms | CE 2; ICE; CES 2; CES2; CES2 protein; Carboxylesterase 2; Carboxylesterase 2 isoform 1 variant; Carboxylesterase 2 precursor… |
| Name | esfenvalerate |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16855054 | Godin SJ, Scollon EJ, Hughes MF, Potter PM, DeVito MJ, Ross MK: Species differences in the in vitro metabolism of deltamethrin and esfenvalerate: differential oxidative and hydrolytic metabolism by humans and rats. Drug Metab Dispos. 2006 Oct;34(10):1764-71. Epub 2006 Jul 19. Results of CE metabolism revealed that human carboxylesterase 1 (hCE-1) was markedly more active toward deltamethrin than the class 1 rat CEs hydrolase A and B and the class 2 human CE (hCE-2); however, hydrolase A metabolized esfenvalerate 2-fold faster than hCE-1, whereas hydrolase B and hCE-1 hydrolyzed esfenvalerate at equal rates. |
81(1,1,1,1) | Details |
| 17442360 | Crow JA, Borazjani A, Potter PM, Ross MK: Hydrolysis of pyrethroids by human and rat tissues: examination of intestinal, liver and serum carboxylesterases. Toxicol Appl Pharmacol. 2007 May 15;221(1):1-12. Epub 2007 Mar 12. Both trans-permethrin and bioresmethrin were effectively cleaved by this serum CE, but deltamethrin, esfenvalerate, alpha-cypermethrin and cis-permethrin were slowly hydrolyzed. The major esterase in human intestine is carboxylesterase 2 (hCE2). |
1(0,0,0,1) | Details |