Protein Information

Name KAT2
Synonyms 2 aminoadipate aminotransferase; 2 aminoadipate transaminase; AADAT; Alpha aminoadipate aminotransferase; Aminoadipate aminotransferase; KAT 2; KAT/AadAT; KAT2…

Compound Information

Name jasmonic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
18441338 Castillo MC, Leon J: Expression of the beta-oxidation gene 3-ketoacyl-CoA thiolase 2 (KAT2) is required for the timely onset of natural and dark-induced leaf senescence in Arabidopsis. J Exp Bot. 2008;59(8):2171-9. Epub 2008 Apr 25.

Among positive regulators, jasmonic acid (JA) accumulates in senescing leaves and the JA-insensitive coi1-1 mutant displays delayed leaf senescence in Arabidopsis.
6(0,0,0,6) Details
15141068 Cruz Castillo M, Martinez C, Buchala A, Metraux JP, Leon J: Gene-specific involvement of beta-oxidation in wound-activated responses in Arabidopsis. Plant Physiol. 2004 May;135(1):85-94.

Mechanical damage triggered the local and systemic induction of only ACX1 among acyl-coenzyme A oxidase (ACX) genes, and KAT2/PED1 among 3-ketoacyl-coenzyme A thiolase (KAT) genes in Arabidopsis.
Although most of the beta-oxidation genes were activated by wound-related factors such as dehydration and abscisic acid, jasmonic acid (JA) induced only ACX1 and KAT5.
3(0,0,0,3) Details
18194426 Castillo MC, Sandalio LM, Del Rio LA, Leon J: Peroxisome proliferation, wound-activated responses and expression of peroxisome-associated genes are cross-regulated but uncoupled in Arabidopsis thaliana. Plant Cell Environ. 2008 Apr;31(4):492-505. Epub 2008 Jan 9.

Among them, peroxisomal beta-oxidation-mediated synthesis of jasmonic acid (JA) is a key process in regulating development as well as wound- or pathogen-triggered defence responses.
The hypolipidemic drug clofibrate (CFB) induced the proliferation of peroxisomes and the expression of the beta-oxidation 3-ketoacyl-CoA thiolase 2 (KAT2) gene, coding for a key enzyme in the biosynthesis of JA, among other wound- and JA-responsive gene transcripts in Arabidopsis leaves.
1(0,0,0,1) Details