Protein Information

Name Ca x
Synonyms CA X; CA RP X; CA RPX; CA10; CARP X; CARPX; Carbonic anhydrase X; Carbonic anhydrase related protein X…

Compound Information

Name phosphorus
CAS phosphorus

Reference List

PubMed Abstract RScore(About this table)
19473635 Ito H, Ogata H, Yamamoto M, Takahashi K, Shishido K, Takahashi J, Taguchi S, Kinugasa E: Comparison of oral falecalcitriol and intravenous calcitriol in hemodialysis patients with secondary hyperparathyroidism: a randomized, crossover trial. Clin Nephrol. 2009 Jun;71(6):660-8.


Serum Ca, P, and Ca x P product levels at the end of each treatment were comparable and the frequencies of hypercalcemia and hyperphosphatemia were also similar during each treatment period.
1(0,0,0,1) Details
20016142 Lund RJ, Andress DL, Amdahl M, Williams LA, Heaney RP: Differential effects of paricalcitol and calcitriol on intestinal calcium absorption in hemodialysis patients. Am J Nephrol. 2010;31(2):165-70. Epub 2009 Dec 11.


There were no significant differences in serum PTH, Ca, phosphorus (P), or Ca x P.
0(0,0,0,0) Details
19736246 Locatelli F, Dimkovic N, Pontoriero G, Spasovski G, Pljesa S, Kostic S, Manning A, Sano H, Nakajima S: Effect of MCI-196 on serum phosphate and cholesterol levels in haemodialysis patients with hyperphosphataemia: a double-blind, randomized, placebo-controlled study. Nephrol Dial Transplant. 2010 Feb;25(2):574-81. Epub 2009 Sep 7.

However, calcium-phosphorus product (Ca x P) was significantly reduced in the 6 and 9 g/day groups P < 0.05).
112(1,2,2,2) Details
19713297 Moore C, Yee J, Malluche H, Rao DS, Monier-Faugere MC, Adams E, Daramola-Ogunwuyi O, Fehmi H, Bhat S, Osman-Malik Y: Relationship between bone histology and markers of bone and mineral metabolism in African-American hemodialysis patients. Clin J Am Soc Nephrol. 2009 Sep;4(9):1484-1493.

At the time of biopsy, mean corrected calcium was 9.1, 8.9, and 9.4 mg/dl (P = 0.344); calcium-phosphorus (Ca X PO4) product was 42, 55, and 62 mg (2)/dl (2) (P = 0.002); phosphorus was 4.6, 6.2, and 6.7 mg/dl (P = 0.005); and iPTH was 225, 566, and 975 pg/ml (P = 0.006), respectively.
87(1,1,2,2) Details
19440993 Petrovic D, Obrenovic R, Stojimirovic B: Risk factors for aortic valve calcification in patients on regular hemodialysis. Int J Artif Organs. 2009 Mar;32(3):173-9.

The variables investigated were: serum albumin, C-reactive protein (CRP), homocysteine, total cholesterol, LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), triglycerides (TG), Apolipoprotein A-I (Apo A-I), Apolipoprotein B (Apo B) and lipoprotein (a), calcium, phosphate and parathormone, and calcium-phosphorus product (Ca x P).
82(1,1,1,2) Details
19369690 Urena P, Jacobson SH, Zitt E, Vervloet M, Malberti F, Ashman N, Leavey S, Rix M, Os I, Saha H, Ryba M, Bencova V, Banos A, Zani V, Fouque D: Cinacalcet and achievement of the NKF/K-DOQI recommended target values for bone and mineral metabolism in real-world clinical practice--the ECHO observational study. Nephrol Dial Transplant. 2009 Sep;24(9):2852-9. Epub 2009 Apr 15.

The proportions of patients achieving the recommended [NKF-K/DOQI (TM) (KDOQI (TM))] targets increased from baseline [4%, 39%, 40% and 46% for iPTH, phosphorus, calcium and calcium-phosphorus product (Ca x P), respectively] to Month 12 (28%, 48%, 51% and 68%, respectively).
82(1,1,1,2) Details
19640383 Liu YL, Wang SM, Lin HH, Wang IK, Kuo HL, Yang YF, Liu JH, Chou CY, Yeh HC, Ting IW, Tsai CA, Huang CC: The relationship between chronic hepatitis B infection and bone mineral, metabolism in peritoneal dialysis patients. Clin Nephrol. 2009 Jul;72(1):15-20.

PATIENTS AND METHODS: Serum calcium [adj], phosphorus, calcium and phosphorus product (Ca x P), along with intact parathyroid hormone (iPTH) levels were compared in peritoneal dialysis patients with and without chronic hepatitis B infection.
81(1,1,1,1) Details
20167032 Ashkar ZM: Association of calcium-phosphorus product with blood pressure in dialysis. J Clin Hypertens. 2010 Feb 1;12(2):96-103.

Linear regression analysis was done between averages of calcium and phosphorus (ca x ph) product and blood pressures (BPs).
33(0,1,1,3) Details
19298641 Abdul Gafor AH, Saidin R, Loo CY, Mohd R, Zainudin S, Shah SA, Norella KC: Intravenous calcitriol versus paricalcitol in haemodialysis patients with severe secondary hyperparathyroidism. Nephrology. 2009 Aug;14(5):488-92. Epub 2009 Mar 10.

Intensive treatment with calcitriol is often complicated by hypercalcaemia, hyperphosphataemia and elevated calcium phosphorus (Ca X PO (4)) product.
32(0,1,1,2) Details
19713292 Wang AY, Lam CW, Wang M, Chan IH, Lui SF, Sanderson JE: Is valvular calcification a part of the missing link between residual kidney function and cardiac hypertrophy in peritoneal dialysis patients?. Clin J Am Soc Nephrol. 2009 Oct;4(10):1629-36. Epub 2009 Aug 27.


Using multiple linear regression analysis, loss of RRF showed significant association with increased LV mass index, but this association was lost after additional adjustment for CRP, Ca x P, and valvular calcification.
2(0,0,0,2) Details
19808245 Navarro-Gonzalez JF, Mora-Fernandez C, Muros M, Herrera H, Garcia J: Mineral metabolism and inflammation in chronic kidney disease patients: a cross-sectional study. Clin J Am Soc Nephrol. 2009 Oct;4(10):1646-54. Epub 2009 Sep 24.


After adjustment for age, gender, and eGFR, the levels of C-reactive protein (CRP) and IL-6 (IL-6) of the third tertile of P, Ca x P, and PTH were significantly higher than those of the first and second tertiles.
2(0,0,0,2) Details
19297359 Davidovich E, Davidovits M, Peretz B, Shapira J, Aframian DJ: The correlation between dental calculus and disturbed mineral metabolism in paediatric patients with chronic kidney disease. Nephrol Dial Transplant. 2009 Aug;24(8):2439-45. Epub 2009 Mar 17.


The lowest salivary Mg was found in the D group while the highest salivary Ca x P product was found in the PrD group.
1(0,0,0,1) Details
19762837 Moreira VR, Zeringue LK, Williams CC, Leonardi C, McCormick ME: Influence of calcium and phosphorus feeding on markers of bone metabolism in transition cows. J Dairy Sci. 2009 Oct;92(10):5189-98.

Pyridinoline concentrations were affected by dietary Ca levels and tended to have a significant dietary Ca x dietary P interaction.
1(0,0,0,1) Details