Protein Information

Name albumin
Synonyms ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619…

Compound Information

Name chlorfenvinphos
CAS 2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl phosphate

Reference List

PubMed Abstract RScore(About this table)
17615116 Carter WG, Tarhoni M, Rathbone AJ, Ray DE: Differential protein adduction by seven organophosphorus pesticides in both brain and thymus. Hum Exp Toxicol. 2007 Apr;26(4):347-53.

We found significant adduction of partially characterized protein targets in both rat brain and thymus by azamethiphos, chlorfenvinphos, chlorpyrifos-oxon, diazinon-oxon, dichlorvos and malaoxon, in vitro and pirimiphos-methyl in vivo.
However, some adducted proteins are also expressed in blood, notably albumin, and so may provide exposure measures to increase the power of future epidemiological studies.
1(0,0,0,1) Details
18484351 Tarhoni MH, Lister T, Ray DE, Carter WG: Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides. Biomarkers. 2008 Jun;13(4):343-63.

At pesticide exposures producing approximately 30% inhibition of AChE, rat plasma albumin binding in vitro by azamethiphos (oxon), chlorfenvinphos (oxon), chlorpyrifos-oxon, diazinon-oxon and malaoxon was reduced from controls by 9+/-1%, 67+/-2%, 56+/-2%, 54+/-2% and 8+/-1%, respectively.
120(1,2,2,10) Details