Name | klotho |
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Synonyms | KL; Klotho; Klotho peptide; Klotho precursor; Klothos; Klotho peptides; Klotho precursors |
Name | phosphorus |
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CAS | phosphorus |
PubMed | Abstract | RScore(About this table) | |
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19345526 | Torres PA: [Origin of the mediacalcosis in kidney failure] . J Mal Vasc. 2009 May;34(3):204-10. Epub 2009 Apr 3. It is now possible to identify factors clearly favoring the formation of VC: TNF-alpha (which stimulates cell necrosis/apoptosis), CRP, oxidized lipids, AGEs, leptin, inorganic high -phosphorus product (CaxPO (4)), 1,25-OH (2) D (3) and (3), PTHrP (via an intracrine pathway), cyclic AMP, TGF-beta, bone morphogenic protein 2 (BMP2) and factors protective against the formation of VC: HDL, inorganic albumin, ahsg/fetuin A, osteopontin (OPN), osteoprotegerin (OPG), osteonectin (ON), bone morphogenic protein 7 (BMP7), klotho, PTHrP (via a paracrine pathway), matrix gla protein (MGP), PTH (via Msx2) and |
31(0,1,1,1) | Details |
19295198 | Nikolov IG, Mozar A, Drueke TB, Massy ZA: Impact of disturbances of metabolism on vascular calcification and clinical outcomes in patients with chronic kidney disease. Blood Purif. 2009;27(4):350-9. Epub 2009 Mar 18. Hypercalcemia and hyperphosphatemia have long been known to play a major role in the occurrence of vascular and other soft tissue calcification in patients with CKD, together with endocrine disturbances including parathyroid hormone, fibroblast growth factor-23, and klotho. It remains to be demonstrated in prospective randomized trials whether normalization of serum phosphorus and/or leads to better patient outcome. |
and 1(0,0,0,1) | Details |
19299893 | Taylor JG, Bushinsky DA: phosphorus homeostasis. Blood Purif. 2009;27(4):387-94. Epub 2009 Mar 23. In addition to parathyroid hormone and recently identified factors such as fibroblast growth factors and klotho play an important role in maintaining mineral ion homeostasis. |
and 1(0,0,0,1) | Details |