Protein Information

Name transferrin
Synonyms Beta 1 metal binding globulin; PRO1400; PRO1557; PRO2086; Serotransferrin; Serotransferrin precursor; Siderophilin; TF…

Compound Information

Name sodium fluoroacetate
CAS sodium 2-fluoroacetate

Reference List

PubMed Abstract RScore(About this table)
4044661 McArdle HJ, Douglas AJ, Bowen BJ, Morgan EH: The mechanism of iron uptake by the rat placenta. . J Cell Physiol. 1985 Sep;124(3):446-50.

Transferrin endocytosis was less susceptible to the effects of metabolic inhibitors such as sodium fluoroacetate, potassium cyanide, 2,4, dinitrophenol or carbonylcyanide M-chlorophenyl hydrazone (CCCP) than was iron uptake.
37(0,1,1,7) Details
831800 Kailis SG, Morgan EH: Iron uptake by immature erythroid cells. Biochim Biophys Acta. 1977 Jan 21;464(2):389-98.

The mechanism by which the utilization of transferrin-bound iron is linked with cellular metabolism was investigated using rabbit reticulocytes and bone marrow cells.
The rate of metabolism was altered by the use of inhibitors which act at different sites in the metabolic pathway (NaF, sodium fluoroacetate, rotenone, 2,4-dinitrophenol, NaCN) and by the addition of metabolic substrates (inosine, sodium pyruvate, sodium lactate).
4(0,0,0,4) Details