| Name | aldehyde dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | aldehyde dehydrogenase; aldehyde dehydrogenases |
| Name | α-chlorohydrin |
|---|---|
| CAS | 3-chloro-1,2-propanediol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10528996 | Hammond AH, Fry JR: Effect of cyanamide on toxicity and depletion in rat hepatocyte cultures: differences between two dichloropropanol isomers. Chem Biol Interact. 1999 Sep 30;122(2):107-15. The effect of aldehyde dehydrogenase inhibition by cyanamide pre-treatment in vitro on dichloropropanol-dependent toxicity and depletion was investigated in 24 h rat hepatocyte cultures. |
2(0,0,0,2) | Details |
| 20056735 | Chen YT, Liao JW, Hung DZ: Protective effects of fomepizole on 2-chloroethanol toxicity. Hum Exp Toxicol. 2010 Jun;29(6):507-12. Epub 2010 Jan 7. In contrast, disulfiram (DSF), an aldehyde dehydrogenase inhibitor, increased the toxicity of 2-CE on the lethality in rats. |
1(0,0,0,1) | Details |
| 16882532 | Bronley-DeLancey A, McMillan DC, McMillan JM, Jollow DJ, Mohr LC, Hoel DG: Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol. Environ Health Perspect. 2006 Aug;114(8):1237-42. CH is metabolized to the hepatocarcinogen trichloroacetate (TCA) by aldehyde dehydrogenase (ALDH) and to the noncarcinogenic metabolite trichloroethanol (TCOH) by alcohol dehydrogenase (ADH). |
1(0,0,0,1) | Details |