Protein Information

Name alkaline phosphatase
Synonyms ALP 1; Alkaline phosphatase; ALPG; ALPPL; ALPPL 2; ALPPL2; GCAP; Germ cell alkaline phosphatase…

Compound Information

Name α-chlorohydrin
CAS 3-chloro-1,2-propanediol

Reference List

PubMed Abstract RScore(About this table)
410636 Dixit VP: Chemical sterilization of male langurs: synergistic action of alpha-chlorohydrin (U-5897) with methallibure (ICI, 33828) on the testes and epididymides of Presbytis entellus entellus Dufresne. Endokrinologie. 1977 Jul;69(2):157-63.


Total cholesterol per gram of testis and alkaline phosphatase activity were increased after alpha-chlorohydrin administration. 4.
1(0,0,0,1) Details
823753 Dixit VP: A reversible chemical sterilization of male langurs (Presbytisentellus entellus Dufresne): a single intratesticular injection of alpha-chlorohydrin. Acta Eur Fertil. 1976 Jun;7(2):175-9.


Serum-aminotransferases, alkaline phosphatase, plasma cholesterol, haemoglobin and hematocrit levels remained within normal limits. 5 - In conclusion, a reversible male sterilization in langurs is of particular importanze with normal liver functions.
1(0,0,0,1) Details
6160048 Kalla NR, Chohan KS: Studies on the mechanism of action of alpha-monochlorohydrin. Exp Pathol. 1980;18(7-8):430-7.


Alkaline phosphatase, SDH, nucleic acids and proteins showed a fall after treatment with the drug.
1(0,0,0,1) Details
824923 Dixit VP, Saxena S: Studies on hepatic function in the male langur (presbytis entellus entellus) following the administration of alpha-chlorohydrin. Acta Biol Med Ger. 1976;35(5):683-6.


The alkaline phosphatase levels were in normal range. 4. alpha-Chlorohydrin administration elevated the liver and plasma cholesterol levels. 5.
1(0,0,0,1) Details
3775778 Hobara T, Kobayashi H, Kawamoto T, Iwamoto S, Hirota S, Shimazu W, Sakai T: Extrahepatic organs metabolism of inhaled trichloroethylene. Toxicology. 1986 Nov;41(3):289-303.


This system maintained nearly normal biochemical and physiological parameters, i.e. arterial blood pressure, heart rate, electrocardiogram, leukocyte and erythrocyte count, hematocrit, alkaline phosphatase, blood urea nitrogen, ammonia and creatinine, for 2 h.
1(0,0,0,1) Details
1509214 Imazu K, Fujishiro K, Inoue N, Koga M, Iwasa T: [Toxicity of dichloropropanols--changes in hematological findings and serum chemistry]. J UOEH. 1992 Mar 1;14(1):73-6.


Transaminases, alkaline phosphatase and lactate dehydrogenase were greatly elevated.
1(0,0,0,1) Details