Name | albumin |
---|---|
Synonyms | ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619… |
Name | α-chlorohydrin |
---|---|
CAS | 3-chloro-1,2-propanediol |
PubMed | Abstract | RScore(About this table) | |
---|---|---|---|
1438041 | Onks DL, Robertson AF, Brodersen R: The effect of chloral hydrate and its metabolites, trichloroethanol and trichloroacetic acid, on -albumin binding. Pharmacol Toxicol. 1992 Sep;71(3 Pt 1):196-7. |
3(0,0,0,3) | Details |
11834892 | Solt K, Johansson JS: Binding of the active metabolite of chloral hydrate, 2,2,2-trichloroethanol, to serum albumin demonstrated using fluorescence quenching. Pharmacology. 2002;64(3):152-9. fluorescence quenching has been used previously to show that halothane and chloroform bind saturably to serum albumin, and a similar approach is used here to demonstrate that TCE also binds to albumin. |
1(0,0,0,1) | Details |
11869834 | Mensing T, Welge P, Voss B, Fels LM, Fricke HH, Bruning T, Wilhelm M: Renal toxicity after chronic inhalation exposure of rats to trichloroethylene. Toxicol Lett. 2002 Mar 10;128(1-3):243-7. Specific parameters related to the renal damage were determined in urine [biomarker for glomerular damage: high molecular weight proteins (HMW), albumin (ALB); for proximal tubular damage: N-acetyl-beta-D-glucosaminidase (NAG), low-molecular-weight-proteins (LMW)]. |
1(0,0,0,1) | Details |
11201665 | De Smet K, Bruning T, Blaszkewicz M, Bolt HM, Vercruysse A, Rogiers V: Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes. Arch Toxicol. 2000 Dec;74(10):587-92. Endpoints studied were albumin secretion and the cytochrome P450 (CYP)-dependent enzymatic activities ethoxyresorufin O-deethylase (EROD), pentoxyresorufin O-depentylase (PROD) and N-nitrosodimethylamine demethylase (NDMA). |
1(0,0,0,1) | Details |