| Name | CHOP |
|---|---|
| Synonyms | 75 kDa DNA pairing protein; FUS1; CHOP; FUS; FUS 1; FUS CHOP; FUS/ATF1fusion gene; FUS/CHOP fusion gene… |
| Name | α-chlorohydrin |
|---|---|
| CAS | 3-chloro-1,2-propanediol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11012786 | Bone W, Cooper TG: In vitro inhibition of rat cauda epididymal sperm glycolytic enzymes by ornidazole, alpha-chlorohydrin and 1-chloro-3-hydroxypropanone. Int J Androl. 2000 Oct;23(5):284-93. The dose-dependent inhibition in vitro of the glycolytic enzymes glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and triosephosphate isomerase (TPI) of distal cauda epididymal rat spermatozoa by (R)-, (S)- and (R,S)-ornidazole (ORN), (R,S)-alpha-chlorohydrin (ACH) and 1-chloro-3-hydroxypropanone (CHOP) was compared. |
4(0,0,0,4) | Details |
| 10886428 | Cooper TG, Jones AR: Metabolism of the putative antifertility agents 3-(36) chloro-1-hydroxypropanone and its dimethyl ketal in the male rat. Int J Androl. 2000 Aug;23(4):243-7. 3-(36) Chloro-1-hydroxypropanone (CHOP), a specific inhibitor of sperm glycolysis in vitro, is rapidly metabolized by the male rat to alpha-chlorohydrin, 3-chlorolactate and the inhibitory sperm metabolite, 3-chlorolactaldehyde, presumably all being of the (S)-configuration. |
2(0,0,0,2) | Details |
| 11330647 | Bone W, Jones AR, Morin C, Nieschlag E, Cooper TG: Susceptibility of glycolytic enzyme activity and motility of spermatozoa from rat, mouse, and human to inhibition by proven and putative chlorinated antifertility compounds in vitro. J Androl. 2001 May-Jun;22(3):464-70. Cells were incubated in a medium containing as the sole energy source with 1-chloro-3-hydroxypropanone (CHOP) and 1,6-dichloro-1,6-dideoxy- (DCDF), chlorinated analogues of glycolytic substrates, as well as racemic (R,S)-alpha-chlorohydrin (ACH). |
2(0,0,0,2) | Details |