Protein Information

Name alcohol dehydrogenase (protein family or complex)
Synonyms ADH; alcohol dehydrogenase; alcohol dehydrogenases

Compound Information

Name nonanol
CAS 3,5,5-trimethyl-1-hexanol

Reference List

PubMed Abstract RScore(About this table)
15733541 Edwards JE, Rose RL, Hodgson E: The metabolism of nonane, a JP-8 jet fuel component, by human liver microsomes, P450 isoforms and alcohol dehydrogenase and inhibition of human P450 isoforms by JP-8. Chem Biol Interact. 2005 Feb 10;151(3):203-11. Epub 2005 Jan 19.

Cytochrome P450 (CYP) isoforms 1A2, 2B6 and 2E1 metabolize nonane to 2-nonanol, whereas alcohol dehydrogenase, CYPs 2B6 and 2E1 metabolize 2-nonanol to 2-nonanone.
82(1,1,1,2) Details
7814397 Sakuraba H, Noguchi T: Alcohol:NAD+ oxidoreductase is present in rat liver peroxisomes. . J Biol Chem. 1995 Jan 6;270(1):37-40.

The distribution of alcohol:NAD+ oxidoreductase activity with nonanol as substrate in the light mitochondrial fraction (peroxisome-enriched fraction) of rat liver was examined by centrifugation in a sucrose density gradient.
The evidence was obtained that the enzyme differed from alcohol dehydrogenases and alcohol oxidizing systems found previously.
1(0,0,0,1) Details