| Name | CA2 |
|---|---|
| Synonyms | CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III… |
| Name | sodium cyanide |
|---|---|
| CAS | sodium cyanide (Na(CN)) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2559376 | Aitken PG, Braitman DJ: The effects of on neural and synaptic function in hippocampal slices. Neurotoxicology. 1989 Summer;10(2):239-47. Transverse slices from guinea pig hippocampi were exposed to micromolar concentrations of sodium cyanide while neural and synaptic function were monitored in the CA1 region. |
84(1,1,1,4) | Details |
| 8963661 | Riepe MW, Schmalzigaug K, Fink F, Oexle K, Ludolph AC: in the pyramidal cell layer of hippocampal regions CA1 and CA3 upon selective inhibition and uncoupling of oxidative phosphorylation. Brain Res. 1996 Feb 26;710(1-2):21-7. Energy metabolism was impaired in submerged rat hippocampal slices using the inhibitors amytal, 3-nitropropionate (3-np), sodium cyanide (1 mM each) and the uncoupling agent 2,4-DNP (200 microM). |
5(0,0,0,5) | Details |
| 9660889 | Hammarstrom AK, Gage PW: Inhibition of oxidative metabolism increases persistent current in rat CA1 hippocampal neurons. J Physiol. 1998 Aug 1;510 ( Pt 3):735-41. Inhibiting oxidative phosphorylation by adding 5 mM sodium cyanide to the pipette solution significantly increased the amplitude of INa,P but had no significant effect on the amplitude of INa,T. 4. |
4(0,0,0,4) | Details |
| 1662712 | Cummins TR, Donnelly DF, Haddad GG: Effect of metabolic inhibition on the excitability of isolated hippocampal CA1 neurons: developmental aspects. J Neurophysiol. 1991 Nov;66(5):1471-82. |
3(0,0,0,3) | Details |
| 16624329 | Matsumoto N, Noda E, Nabekura J: Run down of GABAergic depolarization during metabolic inhibition of rat hippocampal CA1 neurons. Life Sci. 2006 Aug 8;79(11):1021-6. Epub 2006 Mar 21. |
2(0,0,0,2) | Details |
| 8495709 | Izumi Y, Benz AM, Clifford DB, Zorumski CF: effects of sodium nitroprusside in rat hippocampal slices. Exp Neurol. 1993 May;121(1):14-23. Incubation with 3 mM SNP for up to 2 h produced neuronal damage characterized by "nuclear ballooning" in CA3 and CA1 pyramidal neurons and interneurons. |
2(0,0,0,2) | Details |
| 8282607 | Iturriaga R, Mokashi A, Lahiri S: Dynamics of carotid body responses in vitro in the presence of CO2-HCO3-: role of carbonic anhydrase. J Appl Physiol. 1993 Oct;75(4):1587-94. The responses to acidic hypercapnia (PCO2 = 50-60 Torr, pH = 7.20-7.10), hypoxia (PO2 = 25 and 50 Torr), perfusate flow interruption, and bolus injections of sodium cyanide (20-40 nmol) were tested. |
2(0,0,0,2) | Details |
| 9017669 | Doolette DJ: Mechanism of accumulation in the hippocampal slice during energy deprivation. Neurochem Int. 1997 Feb;30(2):211-23. The mechanism by which accumulates in the hippocampal slice during energy deprivation was investigated by examining the adenosine A1 receptor mediated depression of synaptically evoked field potentials in the CA1 area. Blocking of the mitochondrial electron transport chain with 200 microM sodium cyanide or mitochondrial uncoupling with 50 microM 2,4-dinitrophenol both produced a rapid depression of synaptic transmission that was antagonised by 1 microM 8-cyclopentyl-1, 3-dimethylxanthine, an adenosine A1 receptor antagonist. |
1(0,0,0,1) | Details |
| 12042355 | Matsumoto N, Komiyama S, Akaike N: Pre- and postsynaptic ATP-sensitive channels during metabolic inhibition of rat hippocampal CA1 neurons. J Physiol. 2002 Jun 1;541(Pt 2):511-20. |
1(0,0,0,1) | Details |
| 10758095 | Tian GF, Baker AJ: Glycolysis prevents anoxia-induced synaptic transmission damage in rat hippocampal slices. J Neurophysiol. 2000 Apr;83(4):1830-9. The evoked population spike (PS) was extracellularly recorded in the CA1 pyramidal cell layer after stimulation of the Schaffer collaterals. When superfusion ACSF contained 20 mM with or without 1 mM sodium cyanide (NaCN), after 60 min reoxygenation the evoked PS completely recovered even following 120 min anoxia. |
1(0,0,0,1) | Details |
| 9490829 | Nowicky AV, Duchen MR: Changes in [Ca2+] i and membrane currents during impaired mitochondrial metabolism in dissociated rat hippocampal neurons. J Physiol. 1998 Feb 15;507 ( Pt 1):131-45. Perforated whole-cell patch clamp and fluorimetric techniques were combined to examine changes in membrane currents, intracellular ([Ca2+] i) and mitochondrial potential (DeltaPsim) in neurons dissociated from the CA1 subfield of the hippocampus of young rats. 2. |
1(0,0,0,1) | Details |
| 8728840 | Pelster B: Blood acidification in the swimbladder: mechanisms and metabolic pathways. Braz J Med Biol Res. 1995 Nov-Dec;28(11-12):1133-8. A significant decrease in the rate of secretion in the presence of the carbonic anhydrase inhibitor ethoxzolamide indicates that the second major route for the release of protons includes carbonic anhydrase activity and the diffusion of CO2. |
1(0,0,0,1) | Details |
| 9514820 | Bernaudin M, Nouvelot A, MacKenzie ET, Petit E: Selective neuronal vulnerability and specific glial reactions in hippocampal and neocortical organotypic cultures submitted to ischemia. Exp Neurol. 1998 Mar;150(1):30-9. Histological analysis using thionin staining and MAP2 immunostaining showed differences in the temporal profile of neuronal damage in hippocampal and neocortical structures, i.e., in decreasing order, CA1 (7 min) > CA3 and neocortical layers II, III, V, VI (30 min) > DG and neocortical layer IV (60 min). |
1(0,0,0,1) | Details |
| 7065204 | Nakanishi T, Nishioka K, Jarmakani JM: Mechanism of tissue Ca2+ gain during reoxygenation after hypoxia in rabbit myocardium. Am J Physiol. 1982 Mar;242(3):H437-49. Addition of an inhibitor or an uncoupler of mitochondrial respiration [sodium cyanide (5 X 10 (-3) M) or dinitrophenol (5 X 10 (-4) M), respectively] in the perfusate caused significant decreases in reoxygenation-induced tissue Ca2+ gain. |
0(0,0,0,0) | Details |