| Name | CA3 |
|---|---|
| Synonyms | CA III; Carbonic anhydrase C; CA3; CAIII; Car3; Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III… |
| Name | sodium cyanide |
|---|---|
| CAS | sodium cyanide (Na(CN)) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8963661 | Riepe MW, Schmalzigaug K, Fink F, Oexle K, Ludolph AC: in the pyramidal cell layer of hippocampal regions CA1 and CA3 upon selective inhibition and uncoupling of oxidative phosphorylation. Brain Res. 1996 Feb 26;710(1-2):21-7. Energy metabolism was impaired in submerged rat hippocampal slices using the inhibitors amytal, 3-nitropropionate (3-np), sodium cyanide (1 mM each) and the uncoupling agent 2,4-DNP (200 microM). |
5(0,0,0,5) | Details |
| 12911616 | Lee AL, Dumas TC, Tarapore PE, Webster BR, Ho DY, Kaufer D, Sapolsky RM: Potassium channel gene therapy can prevent neuron death resulting from necrotic and apoptotic insults. J Neurochem. 2003 Sep;86(5):1079-88. We found that SK2 or Kv1.1 protected not only against kainate or excitotoxicity but also increased survival after sodium cyanide or staurosporine. In vivo overexpression of either channel in dentate gyrus reduced kainate-induced CA3 lesions. |
1(0,0,0,1) | Details |
| 8495709 | Izumi Y, Benz AM, Clifford DB, Zorumski CF: effects of sodium nitroprusside in rat hippocampal slices. Exp Neurol. 1993 May;121(1):14-23. Incubation with 3 mM SNP for up to 2 h produced neuronal damage characterized by "nuclear ballooning" in CA3 and CA1 pyramidal neurons and interneurons. |
1(0,0,0,1) | Details |
| 10461912 | Phillips RG, Meier TJ, Giuli LC, McLaughlin JR, Ho DY, Sapolsky RM: Calbindin D28K gene transfer via herpes simplex virus amplicon vector decreases hippocampal damage in vivo following insults. J Neurochem. 1999 Sep;73(3):1200-5. Previous studies in this laboratory demonstrated that overexpression of the gene for the -binding protein calbindin D28K, via herpes simplex virus (HSV) amplicon vector, increases the survival of hippocampal neurons in vitro following energetic or excitotoxic insults but not following application of sodium cyanide. We now report that in vivo hippocampal infection with the calbindin D28K HSV vector increases neuronal survival in the dentate gyrus after application of the antimetabolite 3-acetylpyridine and increases transsynaptic neuronal survival in area CA3 following kainic acid neurotoxicity. |
1(0,0,0,1) | Details |
| 9514820 | Bernaudin M, Nouvelot A, MacKenzie ET, Petit E: Selective neuronal vulnerability and specific glial reactions in hippocampal and neocortical organotypic cultures submitted to ischemia. Exp Neurol. 1998 Mar;150(1):30-9. Histological analysis using thionin staining and MAP2 immunostaining showed differences in the temporal profile of neuronal damage in hippocampal and neocortical structures, i.e., in decreasing order, CA1 (7 min) > CA3 and neocortical layers II, III, V, VI (30 min) > DG and neocortical layer IV (60 min). |
1(0,0,0,1) | Details |