| Name | myeloperoxidase |
|---|---|
| Synonyms | 38 kDa MYELOPEROXIDASE; MPO; Myeloperoxidase; Myeloperoxidase precursor; Peroxidase (Myeloperoxidase); Myeloperoxidases; Myeloperoxidase precursors; Peroxidase (Myeloperoxidase)s |
| Name | sodium cyanide |
|---|---|
| CAS | sodium cyanide (Na(CN)) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6256411 | Diamond RD, Haudenschild CC: Monocyte-mediated serum-independent damage to hyphal and pseudohyphal forms of Candida albicans in vitro. J Clin Invest. 1981 Jan;67(1):173-82. Iodination of hyphae, a myeloperoxidase and peroxide-dependent process of monocytes, was similarly inhibited by azide, sodium cyanide, and catalase. |
113(1,2,2,3) | Details |
| 3013778 | Miyasaki KT, Wilson ME, Brunetti AJ, Genco RJ: Oxidative and nonoxidative killing of Actinobacillus actinomycetemcomitans by human neutrophils. Infect Immun. 1986 Jul;53(1):154-60. Oxidative mechanisms contributed significantly, and most of the killing attributable to oxidative mechanisms was inhibited by sodium cyanide, which suggested that the myeloperoxidase- peroxide- system participated in the oxidative process. |
33(0,1,1,3) | Details |
| 3013779 | Miyasaki KT, Wilson ME, Genco RJ: Killing of Actinobacillus actinomycetemcomitans by the human neutrophil myeloperoxidase- peroxide- system. Infect Immun. 1986 Jul;53(1):161-5. Most of the killing attributable to oxidative mechanisms is inhibited by sodium cyanide, which suggests that the myeloperoxidase- peroxide- (MPO-H2O2-Cl-) system may be a key factor in the oxidative killing process. |
32(0,1,1,2) | Details |
| 11401469 | Allegra M, Furtmuller PG, Regelsberger G, Turco-Liveri ML, Tesoriere L, Perretti M, Livrea MA, Obinger C: Mechanism of reaction of with human myeloperoxidase. . Biochem Biophys Res Commun. 2001 Mar 30;282(2):380-6. Steady-state experiments showed that the rate of oxidation of is dependent on the H (2) O (2) concentration, is not affected by superoxide dismutase, and is quickly terminated by sodium cyanide. |
3(0,0,0,3) | Details |
| 6288561 | Yong EC, Klebanoff SJ, Kuo CC: Toxic effect of human polymorphonuclear leukocytes on Chlamydia trachomatis. Infect Immun. 1982 Aug;37(2):422-6. Both chlamydial biotypes were also rapidly inactivated by the cell-free myeloperoxidase-H2O2-halide system. |
2(0,0,0,2) | Details |
| 340471 | Daimond RD, Krzesicki R: Mechanisms of attachment of neutrophils to Candida albicans pseudohyphae in the absence of serum, and of subsequent damage to pseudohyphae by microbicidal processes of neutrophils in vitro. J Clin Invest. 1978 Feb;61(2):360-9. Isolated neutrophil granules damaged pseudohyphae only with added peroxide and halide, and damage occurred only with granule fractions known to contain myeloperoxidase. Damage to Candida by neutrophils was inhibited by agents known to act on neutrophil oxidative microbicidal mechanisms, including sodium cyanide, azide, catalase, superoxide dismutase, and 1, 4 diazobicyclo (2, 2, 2) a singlet quencher. |
1(0,0,0,1) | Details |