Protein Information

Name dopamine D2 receptor
Synonyms D(2) dopamine receptor; D2DR; D2R; DRD 2; DRD2; Dopamine D2 receptor; Dopamine receptor D2; Dopamine D2 receptors…

Compound Information

Name sodium cyanide
CAS sodium cyanide (Na(CN))

Reference List

PubMed Abstract RScore(About this table)
6518343 McQueen DS, Mir AK: Changes in carotid body amine levels and effects of dopamine on respiration in rats treated neonatally with capsaicin. Br J Pharmacol. 1984 Dec;83(4):909-18.

Domperidone, a dopamine D2-receptor antagonist, substantially reduced the respiratory depression caused by dopamine, both in capsaicin-treated and in control animals, suggesting that a D2-receptor was involved in the response.
Substantially less reflex hyperventilation was evoked in capsaicin-treated rats by the peripheral chemoreceptor stimulants hypoxia and sodium cyanide, in comparison with the controls, and domperidone did not increase the responsiveness.
2(0,0,0,2) Details
8181537 Cassel GE, Mjorndal T, Persson SA, Soderstrom E: Effects of cyanide on the striatal dopamine receptor binding in the rat. Eur J Pharmacol. 1993 Dec 1;248(4):297-301.

In order to further elucidate the effects on the central dopaminergic pathways the effects of sodium cyanide on the striatal dopamine D1 and dopamine D2 receptor binding were studied in vitro and after administration of sodium cyanide.
82(1,1,1,2) Details
12923816 Yanamoto K, Hosoi R, Uesaka Y, Abe K, Tsukada H, Inoue O: Intrastriatal microinjection of sodium nitroprusside induces cell death and reduces binding of dopaminergic receptors. Synapse. 2003 Nov;50(2):137-43.


Microinjection of either NOC-18 (50 nmol), another type of NO donor, or sodium cyanide (50 nmol) did not caused cell death.
0(0,0,0,0) Details