Protein Information

Name ferritin (protein family or complex)
Synonyms Ferritin; Ferritins

Compound Information

Name sodium cyanide
CAS sodium cyanide (Na(CN))

Reference List

PubMed Abstract RScore(About this table)
1308986 Balla J, Jacob HS, Balla G, Nath K, Vercellotti GM: Endothelial cell heme oxygenase and ferritin induction by heme proteins: a possible mechanism limiting shock damage. Trans Assoc Am Physicians. 1992;105:1-6.

Heme needs to be released from methemoglobin, since sodium cyanide, haptoglobin, and hemopexin inhibit the induction of these proteins.
5(0,0,0,5) Details
1652594 Mikami T: [Uptake and intracellular metabolism of ferritin by primary cultured rat hepatocytes]. Nippon Ika Daigaku Zasshi. 1991 Jun;58(3):317-28.

In order to study the intracellular metabolism of endocytosed ferritin, the hepatocytes preloaded with 59Fe-125I-double labeled ferritin were incubated at 37 degrees C for 4 h in the ligand-free medium containing 100 mumol/l chloroquine (a lysosomal metabolic inhibitor) or 10 mmol/l sodium cyanide (a mitochondrial metabolic inhibitor).
38(0,1,1,8) Details