Protein Information

Name nNOS
Synonyms Constitutive NOS; NOS1; IHPS 1; IHPS1; N NOS; NC NOS; NOS; NOS type I…

Compound Information

Name sodium cyanide
CAS sodium cyanide (Na(CN))

Reference List

PubMed Abstract RScore(About this table)
11696014 Yoneyama H, Yamamoto A, Kosaka H: Neuronal nitric oxide synthase generates superoxide from the oxygenase domain. Biochem J. 2001 Nov 15;360(Pt 1):247-53.


When l-arginine is depleted, neuronal nitric oxide synthase (nNOS) has been reported to generate superoxide.
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20156578 Cadenas JL, Montero SA, Leal C, Lemus M, Portilla-de Buen E, Alvarado BA, de Alvarez-Buylla ER: Nitric oxide in the hypothalamus-pituitary axis mediates increases in brain glucose retention induced by carotid chemoreceptor stimulation with cyanide in rats. Nitric Oxide. 2010 May 15;22(4):296-303. Epub 2010 Feb 13.

Neuronal nitric oxide synthase (nNOS), which catalyzes the generation of nitric oxide (NO), is expressed by neuron subpopulations in the CNS.
In this study, we explored the potential regulatory role of NO on brain glucose retention induced by carotid body chemoreceptor anoxic stimulation with sodium cyanide (NaCN) which inhibits oxidative metabolism.
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