Protein Information

Name aldehyde oxidases
Synonyms AO; AOH 1; AOH1; AOX 1; AOX1; Aldehyde Oxidase; Aldehyde oxidase 1; Aldeyde oxidase…

Compound Information

Name sodium cyanide
CAS sodium cyanide (Na(CN))

Reference List

PubMed Abstract RScore(About this table)
12673621 Johnson CH, Prigge JT, Warren AD, McEwen JE: Characterization of an alternative oxidase activity of Histoplasma capsulatum. Yeast. 2003 Apr 15;20(5):381-8.

Finally, initial studies of regulation of H. capsulatum AOX1 gene expression demonstrated that RNA abundance was increased after hydrogen peroxide-mediated oxidative stress and after inhibition of mitochondrial electron transport enzymes with antimycin A or sodium cyanide.
34(0,1,1,4) Details
11465044 Vickers S, Polsky SL: The biotransformation of nitrogen containing xenobiotics to lactams. Curr Drug Metab. 2000 Dec;1(4):357-89.

When microsomal preparations are incubated with the appropriate substrate in the presence of sodium cyanide the iminium ion may be trapped to produce a cyano compound.
There is evidence that the iminium ions are oxidized to lactams by aldehyde oxidases (cytosolic molybdenum hydroxylases).
3(0,0,0,3) Details