Protein Information

Name transferrin
Synonyms Beta 1 metal binding globulin; PRO1400; PRO1557; PRO2086; Serotransferrin; Serotransferrin precursor; Siderophilin; TF…

Compound Information

Name sodium cyanide
CAS sodium cyanide (Na(CN))

Reference List

PubMed Abstract RScore(About this table)
2730581 van der Ende A, du Maine A, Schwartz AL, Strous GJ: Effect of ATP depletion and temperature on the transferrin-mediated uptake and release of iron by BeWo choriocarcinoma cells. Biochem J. 1989 May 1;259(3):685-92.

Preincubation of BeWo cells for 15 min with 10 mM-sodium cyanide and 50 mM-2-deoxyglucose prior to the determination of 59Fe release did not alter the amount released into medium (which did not contain a high-affinity iron chelator).
3(0,0,0,3) Details
3179445 Thatte HS, Schrier SL: Comparison of transferrin receptor-mediated endocytosis and drug-induced endocytosis in human neonatal and adult RBCs. Blood. 1988 Nov;72(5):1693-700.

Furthermore, receptor-mediated endocytosis is quantitatively blocked by preincubation of neonatal RBCs with sodium cyanide, whereas cyanide does not inhibit drug-induced endocytosis in either adult or neonatal RBCs.
Morphologic observation of the neonatal RBCs established the fact that only puckered RBCs that exhibited brilliant cresyl blue staining reticulum were capable of undergoing receptor-mediated endocytosis of transferrin.
1(0,0,0,1) Details
2015269 Qian ZM, Morgan EH: Effect of metabolic inhibitors on uptake of non-transferrin-bound iron by reticulocytes. Biochim Biophys Acta. 1991 Apr 9;1073(3):456-62.

5(0,0,0,5) Details