| Name | SNAP |
|---|---|
| Synonyms | RIC 4; RIC4; SEC 9; SEC9; SNAP; SNAP 25; SNAP25; SUP… |
| Name | sodium cyanide |
|---|---|
| CAS | sodium cyanide (Na(CN)) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10523414 | Hammarstrom AK, Gage PW: increases persistent current in rat hippocampal neurons. J Physiol. 1999 Oct 15;520 Pt 2:451-61. A component of the SNP molecule added on its own, 5 mM sodium cyanide (NaCN), increased mean current in excised inside-out patches (Vp = +30 mV) from -0.06 +/- 0.04 to -0.58 +/- 0.21 pA (n = 19). SNAP at 3-100 microM increased the average mean inward current in six inside-out patches from -0.07 +/- 0.02 to -0.30 +/- 0.08 pA (Vp = +30 mV). 5. |
4(0,0,0,4) | Details |
| 12126919 | Mosqueira M, Iturriaga R: Carotid body chemosensory excitation induced by involvement of oxidative metabolism. Respir Physiol Neurobiol. 2002 Aug 1;131(3):175-87. Hypoxia (P (O (2)) approximately equal 30 Torr), NaCN and (1-100 microg) and S-nitroso-N-acetylpenicillamide (SNAP, 300-600 microg) increased f (x). |
3(0,0,0,3) | Details |
| 10037476 | Boullerne AI, Nedelkoska L, Benjamins JA: Synergism of and iron in killing the transformed murine oligodendrocyte cell line N20.1. J Neurochem. 1999 Mar;72(3):1050-60. We observed that N20.1 cells were 30 times more sensitive to SNP than to SNAP. Based on two observations, (a) potentiation of the cytotoxic effect of SNP when coincubated with ferricyanide or ferrocyanide, but not sodium cyanide, and (b) protection by deferoxamine, an iron chelator, we conclude that the greater sensitivity of N20.1 cells to SNP compared with SNAP is due to synergism between NO released and the iron portion of SNP, with the accounting for very little of the cytotoxicity. |
1(0,0,0,1) | Details |
| 12388352 | Valdes V, Mosqueira M, Rey S, Del Rio R, Iturriaga R: Inhibitory effects of NO on carotid body: contribution of neural and endothelial nitric oxide synthase isoforms. Am J Physiol Lung Cell Mol Physiol. 2003 Jan;284(1):L57-68. Epub 2002 Sep 6. SNAP (100 microM) reduced the responses to and NaCN. l-NAME (1 mM) enhanced the responses to and NaCN by increasing their duration, but TRIM (100 microM) only enhanced the responses to high doses of NaCN. |
1(0,0,0,1) | Details |