Protein Information

Name neuropeptide Y
Synonyms NPY; Neuropeptide Y; Neuropeptide Y precursor; PYY 4; PYY4; Y Neuropeptide; Neuropeptide ies; Neuropeptide Y precursors…

Compound Information

Name tetramine
CAS

Reference List

PubMed Abstract RScore(About this table)
1348506 Li W, MacDonald RG, Hexum TD: Role of sulfhydryl groups in Y2 neuropeptide Y receptor binding activity. J Biol Chem. 1992 Apr 15;267(11):7570-5.

Benextramine, a tetramine disulfide, irreversibly inhibits neuropeptide Y (NPY) binding to the 50-kDa Y2 NPY receptor in bovine hippocampus (Li, W., MacDonald, R.
82(1,1,1,2) Details
7647980 Palea S, Corsi M, Rimland JM, Trist DG: Discrimination by benextramine between the NPY-Y1 receptor subtypes present in rabbit isolated vas deferens and saphenous vein. Br J Pharmacol. 1995 May;115(1):3-10.

Tetramine disulphides such as BXT could be useful tools in classifying NPY receptors.
In order to characterize the neuropeptide Y (NPY) Y1 receptors known to be present in rabbit isolated vas deferens and saphenous vein, the pharmacological activity of the selective NPY Y1 receptor agonists, [Leu31,Pro34] NPY and various other peptide agonists, together with the putative NPY antagonist, benextramine, were compared in the two tissues. 2.
1(0,0,0,1) Details