Protein Information

Name PK1
Synonyms Black mamba toxin related protein; PRK 1; PRK1; EG VEGF; EGVEGF; Endocrine gland derived vascular endothelial growth factor; Mambakine; PK1…

Compound Information

Name piperonyl butoxide
CAS 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
9844132 Baliga R, Zhang Z, Baliga M, Ueda N, Shah SV: Role of cytochrome P-450 as a source of catalytic iron in cisplatin-induced nephrotoxicity. Kidney Int. 1998 Nov;54(5):1562-9.

In an in vitro study, the effect of cytochrome P-450 inhibitors, cimetidine or piperonyl butoxide, on cisplatin-induced cytotoxicity and catalytic iron release from LLC-PK1 cells was examined.
37(0,1,2,2) Details
8887268 Baliga R, Zhang Z, Shah SV: Role of cytochrome P-450 in hydrogen peroxide-induced cytotoxicity to LLC-PK1 cells. Kidney Int. 1996 Oct;50(4):1118-24.

A second inhibitor of cytochrome P-450, piperonyl butoxide, had a similar dose-dependent beneficial effect against hydrogen peroxide-induced cell injury.
4(0,0,0,4) Details