| Name | glutathione transferase |
|---|---|
| Synonyms | GST class mu 2; GST 4; GST4; GSTM; GSTM 2; GSTM2; GSTM2 2; GSTmu3… |
| Name | piperonyl butoxide |
|---|---|
| CAS | 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8980035 | Karoly ED, Rose RL, Thompson DM, Hodgson E, Rock GC, Roe RM: Monooxygenase, Esterase, and Glutathione Transferase Activity Associated with Azinphosmethyl Resistance in the Tufted Apple Bud Moth, Platynota idaeusalis. Pestic Biochem Physiol. 1996 Jun;55(2):109-21. Piperonyl butoxide failed to synergize azinphosmethyl toxicity. |
2(0,0,0,2) | Details |
| 15849910 | Magdalena Rodriguez M, Bisset JA, Fernandez D, Omayda P: [Resistance to insecticides in larvae and adults of Aedes aegypti, Havana City: prevalence of A4 esterasa associated with resistance to temephos]. Rev Cubana Med Trop. 2004 Jan-Apr;56(1):54-60. According to the results obtained, by using the SSS tributyl phosphotritiade sinergist (DEF) and piperonyl butoxide, it was demonstrated that the multiple function esterases and oxidases played an important role in the resistance to temephos and fenthion. It was proved that he amplified activity of these enzymes was at an elevated frequency in both people's councils, the same as the glutathione transferase (GST) in one of the 2 people's councils. |
1(0,0,0,1) | Details |
| 8723729 | Lillibridge JH, Amore BM, Slattery JT, Kalhorn TF, Nelson SD, Finnell RH, Bennett GD: Protein-reactive metabolites of carbamazepine in mouse liver microsomes. . Drug Metab Dispos. 1996 May;24(5):509-14. A dependence on cytochrome P450 was shown by a requirement for and inhibition by 1-aminobenzotriazole, piperonyl butoxide, and stiripentol. The addition of glutathione transferases diminished protein adduct formation beyond that seen with alone. |
1(0,0,0,1) | Details |
| 18651917 | Wee CW, Lee SF, Robin C, Heckel DG: Identification of candidate genes for fenvalerate resistance in Helicoverpa armigera using cDNA-AFLP. Insect Mol Biol. 2008 Aug;17(4):351-60. Larvae and adults of this strain manifest approximately 50-fold resistance, which is suppressible by piperonyl butoxide and controlled by the semidominant gene RFen1 previously mapped to AFLP Linkage Group 13. Two cytochrome P450s (CYP337B1 and CYP4S1), one carboxylesterase-like protein and one glutathione transferase were found to be constitutively upregulated in resistant insects. |
1(0,0,0,1) | Details |
| 6491983 | Buckpitt AR, Bahnson LS, Franklin RB: Hepatic and pulmonary microsomal metabolism of naphthalene to adducts: factors affecting the relative rates of conjugate formation. J Pharmacol Exp Ther. 1984 Nov;231(2):291-300. Addition of piperonyl butoxide or SKF 525-A to hepatic microsomal incubations markedly decreased covalent binding of naphthalene metabolites but only slightly decreased adduct formation. |
0(0,0,0,0) | Details |
| 2337416 | Thompson D, Constantin-Teodosiu D, Egestad B, Mickos H, Moldeus P: Formation of conjugates during oxidation of by microsomal fractions of rat liver and lung. Biochem Pharmacol. 1990 May 15;39(10):1587-95. The microsomal reaction was dependent on and and was inhibited by cytochrome P450 inhibitors such as 2-diethylaminoethyl-2,2'-diphenylvalerate (SKF 525-A), alpha-naphthoflavone and piperonyl butoxide. |
0(0,0,0,0) | Details |