Protein Information

Name von Willebrand factor
Synonyms Coagulation factor VIII VWF; F8VWF; VWD; VWF; Von Willebrand factor; von Willebrand factor precursor; Von Willebrand factors; von Willebrand factor precursors

Compound Information

Name piperonyl butoxide
CAS 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
14528908 Duzhak T, Emerson MR, Chakrabarty A, Alterman MA, Levine SM: Analysis of protein induction in the CNS of SJL mice with experimental allergic encephalomyelitis by proteomic screening and immunohistochemistry. Cell Mol Biol (Noisy-le-grand). 2003 Jul;49(5):723-32.

Piperonyl butoxide (PBO) suppresses disease in EAE mice, and it exhibits a dual effect on cytochrome P450s that manifests in a transient inhibitory phase followed by induction.
Coagulation factor VIII is carried and protected by von Willebrand factor.
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