| Name | glucosylceramide synthase |
|---|---|
| Synonyms | Ceramide glucosyltransferase; GCS; GLCT 1; Glucosylceramide synthase; UDP glucose ceramide glucosyltransferase; UGCG; Glucosylceramide synthases; UDP glucose ceramide glucosyltransferases |
| Name | piperonyl butoxide |
|---|---|
| CAS | 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1856614 | Shukla A, Radin NS: Metabolism of D-[3H] threo-1-phenyl-2-decanoylamino-3-morpholino- an inhibitor of synthesis, and the synergistic action of an inhibitor of microsomal monooxygenase. J Lipid Res. 1991 Apr;32(4):713-22. Analysis of mice injected with one or both drugs showed that piperonyl butoxide augmented the effects of PDMP on and dihexosylceramide levels, as well as on the activity of glucosylceramide synthase. |
6(0,0,1,1) | Details |
| 8086032 | Radin NS: Rationales for cancer chemotherapy with PDMP, a specific inhibitor of glucosylceramide synthase. Mol Chem Neuropathol. 1994 Feb-Apr;21(2-3):111-27. PDMP was found to be oxidized by cytochrome P-450, but this process could be blocked in vivo with piperonyl butoxide or cimetidine. |
2(0,0,0,2) | Details |