Protein Information

Name coagulation factor VIII
Synonyms AHF; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII precursor; DXS1253E; F8; F8 protein; F8B…

Compound Information

Name piperonyl butoxide
CAS 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
14528908 Duzhak T, Emerson MR, Chakrabarty A, Alterman MA, Levine SM: Analysis of protein induction in the CNS of SJL mice with experimental allergic encephalomyelitis by proteomic screening and immunohistochemistry. Cell Mol Biol (Noisy-le-grand). 2003 Jul;49(5):723-32.

Piperonyl butoxide (PBO) suppresses disease in EAE mice, and it exhibits a dual effect on cytochrome P450s that manifests in a transient inhibitory phase followed by induction.
Glucose regulated protein 94 (Grp94) and coagulation factor VIII were among the proteins identified in EAE + vehicle and EAE + PBO mice.
2(0,0,0,2) Details