Protein Information

Name IgE
Synonyms IGHE; Ig epsilon chain C region; IgE; immunoglobulin heavy constant epsilon; Ig epsilon chain C regions; IgEs; immunoglobulin heavy constant epsilons

Compound Information

Name piperonyl butoxide
CAS 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
10414782 Diel F, Horr B, Borck H, Savtchenko H, Mitsche T, Diel E: Pyrethroids and piperonyl-butoxide affect human T-lymphocytes in vitro. Toxicol Lett. 1999 Jun 30;107(1-3):65-74.

Although this effect was little compared to histamine liberators like FMLP and anti-IgE, the response to S-bioallethrin and PBO was significantly different in atopic donors compared with non-atopics (P < 0.01).
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7662102 Geller-Bernstein C, Pibourdin JM, Dornelas A, Fondarai J: Efficacy of the acaricide: acardust for the prevention of asthma and rhinitis due to dust mite allergy, in children. Allerg Immunol. 1995 May;27(5):147-54.


At day 0, 90 and 180, total IgE and dust mite specific IgE determination was done.
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12755381 Diel F, Horr B, Borck H, Irman-Florjanc T: Pyrethroid insecticides influence the signal transduction in T helper lymphocytes from atopic and nonatopic subjects. Inflamm Res. 2003 Apr;52(4):154-63.


MATERIAL AND METHODS: PHA-stimulated cultures of T-helper lymphocytes and blood basophil incubates from nonatopic and atopic patients (IgE > 1000 IU) provided cytokine and histamine determination.
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