Protein Information

Name brains
Synonyms BPG dependent PGAM 1; Brain; CDABP0006; PGAM 1; PGAM B; PGAM1; PGAM1 protein; PGAMA…

Compound Information

Name piperonyl butoxide
CAS 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
1842792 Bull DL, Pryor NW: Interactions of carbaryl with susceptible and multiresistant house flies (Diptera: Muscidae). J Econ Entomol. 1991 Aug;84(4):1145-53.

In evaluations of topical toxicity and in vitro metabolic degradation, coadministration of the metabolic synergists piperonyl butoxide (a microsomal oxidase inhibitor) and S,S,S-tributyl phosphorothioate (DEF, an esterase inhibitor) with carbaryl provided conclusive evidence that microsomal oxidases were the major factor in enhanced metabolism and that hydrolytic enzymes had only a minor effect.
These tests also indicated that homogenates of brains from the R strain contained more than one form of AChE with different sensitivities to the inhibitor.
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14522597 Hilscherova K, Blankenship AL, Nie M, Coady KK, Upham BL, Trosko JE, Giesy JP: Oxidative stress in liver and brain of the hatchling chicken (Gallus domesticus) following in ovo injection with TCDD. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Sep;136(1):29-45.


Indicators of oxidative stress were assessed in livers and brains of hatchling chicks.
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