Protein Information

Name cis 2
Synonyms CIS 2; CIS2; Cish2; Cytokine inducible SH2 protein 2; SOCS 2; SOCS2; SSI 2; SSI2…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
19146449 Baciocchi E, Lanzalunga O, Lapi A, Maggini L: Stereochemistry of the C-S bond cleavage in cis-2-methylcyclopentyl phenyl sulfoxide radical cation. J Org Chem. 2009 Feb 20;74(4):1805-8.

The TiO (2) photocatalyzed oxidation of cis-2-methylcyclopentyl phenyl sulfoxide in the presence of Ag (2) SO (4) in MeCN/H (2) O leads to the formation of 1-methylcyclopentanol, 1-methylcyclopentyl acetamide, and phenyl benzenethiosulfonate as the main reaction products.
112(1,2,2,2) Details
20043645 Lu D, Peterson LA: Identification of furan metabolites derived from cysteine-cis-2-butene-1,4-dial-lysine cross-links. Chem Res Toxicol. 2010 Jan;23(1):142-51.

They include the monoglutathione reaction product, N-[4-carboxy-4-(3-mercapto-1H-pyrrol-1-yl)-1-oxobutyl]-l-cysteinylglycine cyclic sulfide, and its downstream metabolite, S-[1-(1,3-dicarboxypropyl)-1H-pyrrol-3-yl] methylthiol, as well as (R)-2-acetylamino-6-(2,5-dihydro-2-oxo-1H-pyrrol-1-yl)-1-hexanoic acid and N-acetyl-S-[1-(5-acetylamino-5-carboxypentyl)-1H-pyrrol-3-yl]-l-cysteine and its sulfoxide.
2(0,0,0,2) Details
19441776 Lu D, Sullivan MM, Phillips MB, Peterson LA: Degraded protein adducts of cis-2-butene-1,4-dial are urinary and hepatocyte metabolites of furan. Chem Res Toxicol. 2009 Jun;22(6):997-1007.

Three additional urinary metabolites of furan were also characterized as follows: R-2-acetylamino-6-(2,5-dihydro-2-oxo-1H-pyrrol-1-yl)-1-hexanoic acid, N-acetyl-S-[1-(5-acetylamino-5-carboxypentyl)-1H-pyrrol-3-yl]-l-cysteine, and its sulfoxide.
2(0,0,0,2) Details