Protein Information

Name survivin
Synonyms API 4; API4; Apoptosis inhibitor 4; Apoptosis inhibitor survivin; BIRC 5; BIRC5; Baculoviral IAP repeat containing protein 5; Baculoviral IAP repeat containing protein 5 isoform 1…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
17965335 Hu H, Shikama Y, Matsuoka I, Kimura J: Terminally differentiated neutrophils predominantly express Survivin-2 alpha, a dominant-negative isoform of survivin. J Leukoc Biol. 2008 Feb;83(2):393-400. Epub 2007 Oct 26.


The subsequent identification of four other alternative splice variants that possess distinct functions and localizations suggested the diverse roles of survivin isoforms.
4(0,0,0,4) Details
17667599 Lopez RA, Goodman AB, Rhodes M, Blomberg JA, Heller J: The anticancer activity of the transcription inhibitor terameprocol (meso-tetra-O-methyl nordihydroguaiaretic acid) formulated for systemic administration. Anticancer Drugs. 2007 Sep;18(8):933-9.


Terameprocol (meso-tetra-O-methyl nordihydroguaiaretic acid, formerly known as EM-1421 and M4N) is a semi-synthetic small molecule with antitumor activity occurring via selective targeting of Sp1-regulated proteins, including survivin and cdc2 that control cell cycle and apoptosis.
1(0,0,0,1) Details