| PubMed |
Abstract |
RScore(About this table) |
| 18942891 |
Hemming ML, Elias JE, Gygi SP, Selkoe DJ: Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements. PLoS Biol. 2008 Oct 21;6(10):e257.
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6(0,0,0,6) |
Details |
| 19414612 |
Inoue E, Deguchi-Tawarada M, Togawa A, Matsui C, Arita K, Katahira-Tayama S, Sato T, Yamauchi E, Oda Y, Takai Y: Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation. J Cell Biol. 2009 May 4;185(3):551-64.
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5(0,0,0,5) |
Details |
| 20026381 |
Yang X, Chen C, Hu Q, Yan J, Zhou C: Gamma-secretase inhibitor (GSI1) attenuates morphological cerebral vasospasm in 24h after experimental subarachnoid hemorrhage in rats. Neurosci Lett. 2010 Jan 29;469(3):385-90. Epub 2009 Dec 22.
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2(0,0,0,2) |
Details |
| 19904829 |
Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG: NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells. 2010 Jan;28(1):5-16.
NOTCH blockade by gamma-secretase inhibitors (GSIs) reduced neurosphere growth and clonogenicity in vitro, whereas expression of an active form of NOTCH2 increased tumor growth. |
1(0,0,0,1) |
Details |
| 18355449 |
Galichet A, Weibel M, Heizmann CW: Calcium-regulated intramembrane proteolysis of the RAGE receptor. . Biochem Biophys Res Commun. 2008 May 23;370(1):1-5. Epub 2008 Mar 18.
Here, we show that sRAGE is also produced through regulated intramembrane proteolysis of the RAGE receptor, which is catalyzed by ADAM10 and the gamma-secretase and that calcium is an essential regulator of RAGE processing. |
1(0,0,0,1) |
Details |