| Name | calpain (protein family or complex) |
|---|---|
| Synonyms | calpain; calpains |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18001554 | Xue HJ, Li WM, Li Y, Gong YT, Sheng L, Zhang L, Chu S: [Effect of calpain 1 on structural remodeling and contractile dysfunction in atrial fibrillation: experiment with dogs]. Zhonghua Yi Xue Za Zhi. 2007 Aug 28;87(32):2285-8. |
7(0,0,0,7) | Details |
| 19126269 | Pereira FM, Elias CG, d'Avila-Levy CM, Branquinha MH, Santos AL: peptidases in Herpetomonas samuelpessoai are modulated by temperature and dimethylsulfoxide-triggered differentiation. Parasitology. 2009 Jan;136(1):45-54. The possible immunological similarity of H. samuelpessoai proteins with well-known peptidases produced by trypanosomatid pathogens, including cruzipain (Trypanosoma cruzi) and peptidase b (cpb) from Leishmania mexicana, was also investigated, as well as with calpain molecules. |
2(0,0,0,2) | Details |
| 19575128 | Colak A, Kaya M, Karaoglan A, Sagmanligil A, Akdemir O, Sahan E, Celik O: Calpain inhibitor AK 295 inhibits calpain-induced apoptosis and improves neurologic function after traumatic spinal cord injury in rats. Neurocirugia. 2009 Jun;20(3):245-54. |
2(0,0,0,2) | Details |
| 20091771 | Sribnick EA, Samantaray S, Das A, Smith J, Matzelle DD, Ray SK, Banik NL: Postinjury treatment of chronic spinal cord injury improves locomotor function in rats. J Neurosci Res. 2010 Jan 20. treatment reduced COX-2 activity, blocked nuclear factor-kappaB translocation, prevented glial reactivity, attenuated neuron death, inhibited activation and activity of calpain and caspase-3, decreased axonal damage, reduced myelin loss in the lesion and penumbra, and improved locomotor function compared with vehicle-treated animals. |
1(0,0,0,1) | Details |
| 17525209 | Perche O, Doly M, Ranchon-Cole I: Caspase-dependent apoptosis in light-induced retinal degeneration. . Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2753-9. Caspase-1, caspase-3, and calpain activities were measured before and 1 day after exposure to the damaging light. |
1(0,0,0,1) | Details |
| 20101028 | Shimotake J, Derugin N, Wendland M, Vexler ZS, Ferriero DM: Vascular endothelial growth factor receptor-2 inhibition promotes cell death and limits endothelial cell proliferation in a neonatal rodent model of stroke. Stroke. 2010 Feb;41(2):343-9. Furthermore, receptor inhibition was associated with increased VEGFR2 expression 5 days after injury (P <0.05) and increased spectrin cleavage with a shift in favor of the calpain-mediated, caspase-3-independent cleavage (P <0.01). |
1(0,0,0,1) | Details |