Protein Information

Name angiotensin II
Synonyms AGT; ANG II; ANHU; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensinogen precursor; SERPINA 8…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
18834172 Preto MA, Melo A, Rodrigues LM, Maia HL, Ramos MJ: Structural insight on the activity of type 1 angiotensin II peptide antagonists using MD simulations. J Phys Chem B. 2008 Oct 30;112(43):13620-8. Epub 2008 Oct 4.

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18626888 Ulleras E, Ohlsson A, Oskarsson A: Secretion of cortisol and aldosterone as a vulnerable target for adrenal endocrine disruption - screening of 30 selected chemicals in the human H295R cell model. J Appl Toxicol. 2008 Nov;28(8):1045-53.


The effect of chemicals was analyzed for basal and forskolin- or angiotensin II-stimulated hormone secretion.
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18455987 Erickson JR, Joiner ML, Guan X, Kutschke W, Yang J, Oddis CV, Bartlett RK, Lowe JS, O'Donnell SE, Aykin-Burns N, Zimmerman MC, Zimmerman K, Ham AJ, Weiss RM, Spitz DR, Shea MA, Colbran RJ, Mohler PJ, Anderson ME: A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell. 2008 May 2;133(3):462-74.


CaMKII is activated by angiotensin II (AngII)-induced oxidation, leading to apoptosis in cardiomyocytes both in vitro and in vivo.
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