| Name | CYP1B1 |
|---|---|
| Synonyms | CP1B; CYP1B1; CYPIB 1; CYPIB1; Cytochrome P450 1B1; GLC3A; Cytochrome P450 1B1s |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19494032 | Jenny MJ, Karchner SI, Franks DG, Woodin BR, Stegeman JJ, Hahn ME: Distinct roles of two zebrafish AHR repressors (AHRRa and AHRRb) in embryonic development and regulating the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci. 2009 Aug;110(2):426-41. Epub 2009 Jun 3. In embryos, dual knockdown of AHRRs, or knockdown of AHRRb alone, enhanced the induction of CYP1A, CYP1B1, and CYP1C1 by TCDD and decreased the constitutive expression of Sox9b. |
1(0,0,0,1) | Details |
| 20090406 | Neis MM, Wendel A, Wiederholt T, Marquardt Y, Joussen S, Baron JM, Merk HF: Expression and induction of cytochrome p450 isoenzymes in human skin equivalents. Skin Pharmacol Physiol. 2010;23(1):29-39. Epub 2010 Jan 14. The expression of CYP1A1 and CYP1B1 was highly inducible by treatment with liquor carbonis detergens. |
1(0,0,0,1) | Details |
| 19497421 | Vondracek J, Krcmar P, Prochazkova J, Trilecova L, Gavelova M, Skalova L, Szotakova B, Buncek M, Radilova H, Kozubik A, Machala M: The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells. Chem Biol Interact. 2009 Jul 15;180(2):226-37. Epub 2009 Mar 27. We report here that, apart from induction of CYP1A1 and CYP1B1 expression and the corresponding enzymatic activity, both BaP and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced rat 3alpha-hydroxysteroid dehydrogenase (AKR1C9) expression and activity. |
2(0,0,0,2) | Details |
| 19684285 | Kim S, Dere E, Burgoon LD, Chang CC, Zacharewski TR: Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells. Toxicol Sci. 2009 Nov;112(1):229-44. Epub 2009 Aug 14. Most genes exhibited dose-dependent responses including CYP1A1, CYP1B1, ALDH1A3, and SLC7A5 genes. |
1(0,0,0,1) | Details |