Protein Information

Name CYP3A5
Synonyms CP35; PCN 3; PCN3; CYP3A5; CYPIIIA 5; CYPIIIA5; Cytochrome P450 3A5; Cytochrome P450 subfamily 3A polypeptide 5…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
19022943 Bakken GV, Rudberg I, Christensen H, Molden E, Refsum H, Hermann M: Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5. Drug Metab Dispos. 2009 Feb;37(2):254-8. Epub 2008 Nov 20.

Formation of the metabolites quetiapine sulfoxide, N-desalkylquetiapine, O-desalkylquetiapine, and 7-hydroxyquetiapine by CYP3A4 and CYP3A5 were compared in the different microsomal preparations.
41(0,1,1,11) Details