Protein Information

Name apoA I
Synonyms APOA 1; APOA1; Apo AI; ApoA I; Apolipoprotein A I; Apolipoprotein A I precursor; Apolipoprotein of high density lipoprotein; Apo AIs…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
20133843 Wong YQ, Binger KJ, Howlett GJ, Griffin MD: Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein A-I. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1977-82. Epub 2010 Jan 19.

9(0,0,0,9) Details
18202432 Brock JW, Jenkins AJ, Lyons TJ, Klein RL, Yim E, Lopes-Virella M, Carter RE, Thorpe SR, Baynes JW: Increased methionine sulfoxide content of apoA-I in type 1 diabetes. J Lipid Res. 2008 Apr;49(4):847-55. Epub 2008 Jan 17.

6(0,0,0,6) Details
18719109 Shao B, Cavigiolio G, Brot N, Oda MN, Heinecke JW: Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12224-9. Epub 2008 Aug 21.

6(0,0,0,6) Details
18832772 Wang XS, Shao B, Oda MN, Heinecke JW, Mahler S, Stocker R: A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL. J Lipid Res. 2009 Mar;50(3):586-94. Epub 2008 Oct 2.


A wide range of reactive intermediates oxidizes methionine residues to methionine sulfoxide (MetO) in apolipoprotein A-I (apoA-I), the major HDL protein.
4(0,0,0,4) Details