Protein Information

Name interleukin (protein family or complex)
Synonyms Interleukin; Interleukins; interleukin receptor; interleukin receptors

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
19966493 Saegusa S, Totsuka M, Kaminogawa S, Hosoi T: Saccharomyces cerevisiae and Candida albicans stimulate cytokine secretion from human neutrophil-like HL-60 cells differentiated with retinoic acid or dimethylsulfoxide. Biosci Biotechnol Biochem. 2009 Dec;73(12):2600-8. Epub 2009 Dec 7.


Intact and heat-killed S. cerevisiae enhanced secretion of interleukin (IL)-1beta, IL-6, IL-8, IL-12, IL-18, MCP-1/CCL2 and TNF-alpha from retinoic acid-treated HL-60 cells, accompanied by alterations in mRNA expression of the cytokines.
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17639882 Iseda K, Ono S, Onoda K, Satoh M, Manabe H, Nishiguchi M, Takahashi K, Tokunaga K, Sugiu K, Date I: Antivasospastic and antiinflammatory effects of caspase inhibitor in experimental subarachnoid hemorrhage. J Neurosurg. 2007 Jul;107(1):128-35.


Interleukin (IL)-1 in the cerebrospinal fluid (CSF) was examined using Western blotting, and brains were immunohistochemically examined for caspase-1 and IL-1beta.
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17380792 Dugo L, Collin M, Allen DA, Patel NS, Bauer I, Mervaala E, Louhelainen M, Foster SJ, Yaqoob MM, Thiemermann C: Inhibiting glycogen synthase kinase 3beta in sepsis. . Novartis Found Symp. 2007;280:128-42; discussion 142-6


GSK-3beta inhibition reduced the increase in NF-kappaB p65 activity caused by interleukin (IL) 1 in human e mbryonic kidney cells in vitro.
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19878061 Akkok CA, Liseth K, Hervig T, Ryningen A, Bruserud O, Ersvaer E: Use of different DMSO concentrations for cryopreservation of autologous peripheral blood stem cell grafts does not have any major impact on levels of leukocyte- and platelet-derived soluble mediators. Cytotherapy. 2009;11(6):749-60.


Low or undetectable levels of leukocyte-derived interleukin (IL)-6 and tumor necrosis factor (TNF)-alpha and CXCL8, high levels of platelet-derived CCL5 and CXCL4, and high levels of monocyte-derived soluble CD14 were measured independent of the DMSO concentration, except for slightly increased CXCL8 and decreased CXCL4 levels with 2% DMSO.
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18005266 Ratthe C, Girard D: Investigation of the interleukin (IL)-4/IL-4 receptor system in promyelocytic leukaemia PLB-985 cells during differentiation toward neutrophil-like phenotype: mechanism involved in IL-4-induced SOCS3 protein expression. 160-4.

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