| Name | estrogen receptor |
|---|---|
| Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18979088 | Fechner P, Proll F, Carlquist M, Proll G: An advanced biosensor for the prediction of estrogenic effects of endocrine-disrupting chemicals on the estrogen receptor alpha. Anal Bioanal Chem. 2009 Mar;393(6-7):1579-85. Epub 2008 Nov 1. |
2(0,0,0,2) | Details |
| 17875331 | Mortensen AS, Arukwe A: Effects of 17alpha- on hormonal responses and xenobiotic biotransformation system of Atlantic salmon (Salmo salar). Aquat Toxicol. 2007 Nov 30;85(2):113-23. Epub 2007 Aug 17. Our data show that EE2 produced time- and concentration-specific modulation of estrogen receptor isoforms (ERalpha, ERbeta) and androgen receptor-beta (ARbeta). |
2(0,0,0,2) | Details |
| 19499261 | Frische T, Faust M, Meyer W, Backhaus T: Toxic masking and synergistic modulation of the estrogenic activity of chemical mixtures in a yeast screen (YES). Environ Sci Pollut Res Int. 2009 Jul;16(5):593-603. Epub 2009 Jun 5. DISCUSSION: The modified YES proved to be a reliable system for the simultaneous quantification of yeast toxicity and estrogen receptor activation. |
1(0,0,0,1) | Details |
| 18632874 | Davis AM, Mao J, Naz B, Kohl JA, Rosenfeld CS: Comparative effects of methyl-piperidino-pyrazole, raloxifene, and ICI 182 780 on gene expression in the murine uterus. J Mol Endocrinol. 2008 Oct;41(4):205-17. Epub 2008 Jul 16. Selective estrogen receptor modulators (SERMs) are potentially useful in treating various endometrial disorders, including endometrial cancer, as they block some of the detrimental effects of |
1(0,0,0,1) | Details |
| 20022167 | Yamada K, Terasaki M, Makino M: A novel estrogenic compound transformed from fenthion under UV-A irradiation. J Hazard Mater. 2010 Apr 15;176(1-3):685-91. The photo-transformed products of fenthion well-known as one of the most photosensitive organophosphorus insecticides and their estrogenic activities were investigated using a yeast two-hybrid assay incorporating the human estrogen receptor alpha (hERalpha). We identified fenthion sulfoxide and 3-methyl-4-methylsulfinylphenol (MMS) as the major transformed products and 3-methyl-4-(methylthio) (MMP) as the minor product under UV-A irradiation. |
1(0,0,0,1) | Details |
| 17919800 | Ju YH, Doerge DR, Helferich WG: A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of -dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice. Food Chem Toxicol. 2008 Jan;46(1):310-20. Epub 2007 Aug 17. We hypothesize that Avlimil could modulate the growth of estrogen receptor positive human breast cancer (MCF-7) cells in vitro and in vivo. |
1(0,0,0,1) | Details |
| 17344101 | Mortensen AS, Arukwe A: Modulation of xenobiotic biotransformation system and hormonal responses in Atlantic salmon (Salmo salar) after exposure to tributyltin (TBT). Comp Biochem Physiol C Toxicol Pharmacol. 2007 Apr;145(3):431-41. Epub 2007 Feb 2. Our data show that TBT produced concentration-specific decrease of estrogen receptor-alpha (ERalpha), vitellogenin (Vtg), zona radiata protein (Zr-protein) and increase of estrogen receptor-beta (ERbeta) and androgen receptor-beta (ARbeta) in the hormonal pathway. |
1(0,0,0,1) | Details |