Name | lactate dehydrogenase (protein family or complex) |
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Synonyms | LDH; lactate dehydrogenase; lactate dehydrogenases |
Name | sulfoxide |
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CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
PubMed | Abstract | RScore(About this table) | |
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20104500 | Terry C, Dhawan A, Mitry RR, Lehec SC, Hughes RD: Optimization of the cryopreservation and thawing protocol for human hepatocytes for use in cell transplantation. Liver Transpl. 2010 Feb;16(2):229-37. The effects on thawed cell viability and attachment, lactate dehydrogenase release, cytochrome P450 1A1/2 activity, and albumin synthesis were determined. |
2(0,0,0,2) | Details |
19945446 | Bergandi L, Aina V, Garetto S, Malavasi G, Aldieri E, Laurenti E, Matera L, Morterra C, Ghigo D: inhibit oxidative pathway and glucose 6-phosphate dehydrogenase activity in human osteoblasts. Chem Biol Interact. 2010 Feb 12;183(3):405-15. Epub 2009 Nov 27. A 24h incubation with 50 microg/ml (12.5 microg/cm (2)) of -containing bioactive glasses termed HCaCaF (2) (F content: 5, 10 and 15 mol.%) caused the release of lactate dehydrogenase in the extracellular medium (index of cytotoxicity), the accumulation of intracellular malonyldialdehyde (index of lipoperoxidation), and the increase of consumption. |
-containing bioactive glasses 1(0,0,0,1) | Details |
20029958 | Tanwar V, Sachdeva J, Kishore K, Mittal R, Nag TC, Ray R, Kumari S, Arya DS: Dose-dependent actions of myocardial necrosis: a biochemical, histopathological, and electron microscopic evidence. Cell Biochem Funct. 2010 Jan;28(1):74-82. There was an increase in superoxide dismutase (SOD), kinase-MB (CK-MB) and lactate dehydrogenase (LDH) levels, decrease in thiobarbituric acid reactive substances (TBARS), and preservation of myocardial architecture in the (100 and 200 mg/kg) treated groups. |
in experimentally induced 1(0,0,0,1) | Details |
18273562 | Mishra P, Kale RK, Kar A: Chemoprevention of mammary tumorigenesis and chemomodulation of the antioxidative enzymes and peroxidative damage in prepubertal Sprague Dawley rats by Mol Cell Biochem. 2008 May;312(1-2):1-9. Epub 2008 Feb 14. Spectrophotometric enzyme estimations revealed that the specific activities of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), peroxidase (GPx), glutathione transferase (GST), DT-diaphorase (DTD), and (GSH) levels were increased, whereas specific activities of lactate dehydrogenase (LDH) and lipid peroxidation (LPO) were decreased significantly, both in liver as well as in mammary gland, in animals treated with prepubertally. |
1(0,0,0,1) | Details |
18679782 | Wang Z, Li M, Wu WK, Tan HM, Geng DF: Ginsenoside Rb1 preconditioning protects against myocardial infarction after regional ischemia and reperfusion by activation of phosphatidylinositol-3-kinase signal transduction. Cardiovasc Drugs Ther. 2008 Dec;22(6):443-52. Epub 2008 Aug 5. Plasma kinase (CK), kinase isoenzyme MB (CK-MB), lactate dehydrogenase (LDH), and troponin T levels were also measured. |
1(0,0,0,1) | Details |
17803263 | Doran JA, O'Donnell JS, Lairson LL, McDonald MR, Schwan AL, Grodzinski B: S-alk (en) yl- Background levels varied depending on the assay used, ranging from 0.4 (lactate dehydrogenase) to 1.5 (high-performance liquid chromatography, HPLC) micromol g (-1) fresh weight (FW) on average. Profiles were composed of (-/+)-methyl-, (-/+)-ethyl-, (+)-propyl-, and (+)-1-propenyl- sulfoxide (MCSO, ECSO, PCSO, and 1-PeCSO, respectively). (+)-PCSO was the most prominent in green (2.4 mg g (-1) FW), yellow (5.5 mg g (-1) FW), and white (3.8 mg g (-1) FW) tissues. |
sulfoxides and relative pungency measurements of photosynthetic and nonphotosynthetic tissues of Allium porrum. J Agric Food Chem. 2007 Oct 3;55(20):8243-50. Epub 2007 Sep 6.1(0,0,0,1) | Details |
17549591 | Silva AR, Pinheiro AM, Souza CS, Freitas SR, Vasconcellos V, Freire SM, Velozo ES, Tardy M, El-Bacha RS, Costa MF, Costa SL: The activation and regulates TNF-alpha and NO release in primary glial cell cultures. Cell Biol Toxicol. 2008 Jan;24(1):75-86. Epub 2007 Jun 5. However, an increased lactate dehydrogenase activity was detected in the culture medium of both culture systems when treated with 100 micromol/L rutin, suggesting loss of cell membrane integrity. |
rutin induces astrocyte and microglia 1(0,0,0,1) | Details |
18197582 | Zimmermann S, Zarse K, Schulz TJ, Siems K, Muller-Kuhrt L, Birringer M, Ristow M: A cell-based high-throughput assay system reveals modulation of oxidative and nonoxidative metabolism due to commonly used organic solvents. Horm Metab Res. 2008 Jan;40(1):29-37. uptake from the supernatant media was quantified by the oxidase method, and L-lactate production of cells was quantified by the lactate dehydrogenase method applied on supernatant media. |
1(0,0,0,1) | Details |