Protein Information

Name lecithin:cholesterol acyltransferase
Synonyms LCAT; LAT; Lecithin cholesterol acyltransferase; Phosphatidylcholine sterol acyltransferase; Phosphatidylcholine sterol acyltransferase precursor; Phospholipid cholesterol acyltransferase; Lecithin cholesterol acyltransferases; Phosphatidylcholine sterol acyltransferases…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
18719109 Shao B, Cavigiolio G, Brot N, Oda MN, Heinecke JW: Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12224-9. Epub 2008 Aug 21.


This pathway is critically dependent on lecithin:cholesterol acyltransferase (LCAT), which rapidly converts cholesterol to cholesteryl ester.
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