Protein Information

Name CD62P
Synonyms CD62; CD62P; CD62P antigen; GMP 140; GMP140; GMRP; GRMP; Granule membrane protein 140…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
18458510 Lee JH, Kim JT, Cho YG: [Effect of nitric oxide on the cryopreservation of platelets] . Korean J Lab Med. 2008 Apr;28(2):136-43.


BACKGROUND: To determine whether nitric oxide (NO) could inhibit activation of platelets stored in a cold or frozen state, we measured platelet P-selectin expression and platelet-bound fibrinogen in platelet-rich plasma (PRP) with S-nitrosoglutathione (GSNO) (Sigma, USA) by flow cytometry.
3(0,0,0,3) Details
18680547 Hornsey VS, McMillan L, Morrison A, Drummond O, Macgregor IR, Prowse CV: Freezing of buffy coat-derived, leukoreduced platelet concentrates in 6 percent dimethyl sulfoxide. Transfusion. 2008 Dec;48(12):2508-14. Epub 2008 Aug 1.


Assays included hypotonic shock response (HSR); aggregation; glycoprotein (GP) Ibalpha and P-selectin binding sites; annexin V binding to phosphatidylserine, glycocalicin, and lactate dehydrogenase (LDH).
2(0,0,0,2) Details
17493358 Yang HY, Tian W, Guo Y, Zhang RL, Zhang WG: [Experimental study on cryopreservation of platelets] . Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Apr;15(2):408-11.


The study was purposed to develop a novel cryopreserved agent (CPA) for platelets, to investigate the morphology of cryopreserved platelets in different CPA and the CD62P expression on membrane of platelets after stimulating by thrombin, as well as to compare the effect of adding UDP-Gal on preserved efficiency of preservation solutions.
2(0,0,0,2) Details
19175732 Appleman EH, Sachais BS, Patel R, Drobatz KJ, Groman RP, Kennedy DR, O'Donnell PA, Bryan C, Callan MB: Cryopreservation of canine platelets. . J Vet Intern Med. 2009 Jan-Feb;23(1):138-45.


Cryopreserved platelets could be activated, as based on mean thrombin-stimulated P-selectin expression (6% DMSO, 23.0%; Thrombosol, 18.4%), although to a lesser extent than fresh PC (49.1%) (P < .0001).
1(0,0,0,1) Details