| Name | caspase 9 |
|---|---|
| Synonyms | APAF 3; APAF3; Apoptotic protease MCH6; Apoptotic protease Mch 6; Apoptotic protease activating factor 3; CASP 9; CASP9; CASPASE 9c… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18586875 | Sharma A, Neekhra A, Gramajo AL, Patil J, Chwa M, Kuppermann BD, Kenney MC: Effects of Benzo (e) Pyrene, a toxic component of cigarette smoke, on human retinal pigment epithelial cells in vitro. Invest Ophthalmol Vis Sci. 2008 Nov;49(11):5111-7. Epub 2008 Jun 27. Activities of caspase-3/7, caspase-8, caspase-9, and caspase-12 were measured by a fluorescence image scanner, and DNA laddering was evaluated by electrophoresis on 3% agarose gel. |
1(0,0,0,1) | Details |
| 19049974 | Maity P, Bindu S, Dey S, Goyal M, Alam A, Pal C, Mitra K, Bandyopadhyay U: Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: a novel role of mitochondrial aconitase oxidation. J Biol Chem. 2009 Jan 30;284(5):3058-68. Epub 2008 Dec 2. The scavengers also restore indomethacin-induced activation of caspase-9 and caspase-3 to block mitochondrial pathway of apoptosis and gastric mucosal damage. |
1(0,0,0,1) | Details |
| 18563491 | Ning L, Jaskula-Sztul R, Kunnimalaiyaan M, Chen H: Suberoyl bishydroxamic acid activates notch1 signaling and suppresses tumor progression in an animal model of medullary thyroid carcinoma. Ann Surg Oncol. 2008 Sep;15(9):2600-5. Epub 2008 Jun 18. Importantly, SBHA treatment resulted in an increase in protein levels of p21 (CIP1/WAF1), p27 (KIP1), cleaved caspase-9, cleaved caspase-3, and cleaved poly ADP- polymerase and concomitant with a decrease in cyclin D1 and cyclin B1, indicating that the growth inhibition was due to both cell cycle arrest and apoptosis. |
1(0,0,0,1) | Details |
| 19012662 | Martin-Renedo J, Mauriz JL, Jorquera F, Ruiz-Andres O, Gonzalez P, Gonzalez-Gallego J: induces cell cycle arrest and apoptosis in hepatocarcinoma HepG2 cell line. J Pineal Res. 2008 Nov;45(4):532-40. Proapoptotic effects of were related to cytosolic cytochrome c release, upregulation of Bax and induction of caspase-9 activity. |
1(0,0,0,1) | Details |
| 18207679 | Qi W, Ding D, Salvi RJ: Cytotoxic effects of (DMSO) on cochlear organotypic cultures. Hear Res. 2008 Feb;236(1-2):52-60. Epub 2007 Dec 15. DMSO treatment induced TUNEL-positive staining in many hair cells and activated both initiator caspase-9 and caspase-8 and executioner caspase-3; this suggests that apoptosis is initiated by both intrinsic mitochondrial and extrinsic membrane cell death signaling pathways. |
1(0,0,0,1) | Details |