| Name | bcl 2 |
|---|---|
| Synonyms | Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19358267 | Onori P, DeMorrow S, Gaudio E, Franchitto A, Mancinelli R, Venter J, Kopriva S, Ueno Y, Alvaro D, Savage J, Alpini G, Francis H: phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-kappaB and induction of apoptosis. Int J Cancer. 2009 Aug 1;125(3):565-76. Bax expression was increased, whereas Bcl-2 was decreased in cells treated with CAPE compared to vehicle. |
1(0,0,0,1) | Details |
| 19499887 | Joubert A, Marais S, Maritz C: Influence of on MCF-7 cells: an improved differential interference contrasting technique and Bcl-2 and Bax protein expression levels. Biocell. 2009 Apr;33(1):67-70. |
1(0,0,0,1) | Details |
| 20167109 | Galuppo M, Di Paola R, Mazzon E, Genovese T, Crisafulli C, Paterniti I, Cuzzocrea E, Bramanti P, Kapoor A, Thiemermann C, Cuzzocrea S: Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study. J Inflamm. 2010 Feb 18;7:12. In pancreas, lung and gut, immunohistochemical analysis of some end points of the inflammatory response, such as inducible synthase (iNOS), nitrotyrosine, poly (ADP- (PAR), TNF- and IL-1as well as FasL, Bax, Bcl-2 and apoptosis, revealed positive staining in sections of tissue obtained from zymosan-injected mice. |
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| 17532791 | Chen C, Hu Q, Yan J, Lei J, Qin L, Shi X, Luan L, Yang L, Wang K, Han J, Nanda A, Zhou C: Multiple effects of 2ME2 and D609 on the cortical expression of HIF-1alpha and apoptotic genes in a middle cerebral artery occlusion-induced focal ischemia rat model. J Neurochem. 2007 Sep;102(6):1831-41. Epub 2007 May 26. At 24 h, 2ME2 and D609 reduce the levels of HIF-1alpha and VEGF (enzyme-linked immunosorbent assay), depress the expression of HIF-1alpha, VEGF, BCL2/adenovirus E1B 19 kDa interacting protein 3 (BNIP3) and cleaved caspase 3 (western blot and immunohistochemistry) in the brain infarct area. |
1(0,0,0,1) | Details |
| 19062170 | Soto P, Smith LC: BH4 peptide derived from Bcl-xL and Bax-inhibitor peptide suppresses apoptotic mitochondrial changes in heat stressed bovine oocytes. Mol Reprod Dev. 2009 Jul;76(7):637-46. Mitochondria play an important role in the integration and transmission of cell death signals mediated by the Bcl-2 family proteins. |
1(0,0,0,1) | Details |
| 19785986 | Zhuo L, Gong J, Yang R, Sheng Y, Zhou L, Kong X, Cao K: Inhibition of proliferation and differentiation and promotion of apoptosis by cyclin L2 in mouse embryonic carcinoma P19 cells. Biochem Biophys Res Commun. 2009 Dec 18;390(3):451-7. Epub 2009 Sep 26. The anti-apoptotic Bcl-2 protein was also downregulated in these cells. |
1(0,0,0,1) | Details |
| 18563491 | Ning L, Jaskula-Sztul R, Kunnimalaiyaan M, Chen H: Suberoyl bishydroxamic acid activates notch1 signaling and suppresses tumor progression in an animal model of medullary thyroid carcinoma. Ann Surg Oncol. 2008 Sep;15(9):2600-5. Epub 2008 Jun 18. Moreover, SBHA downregulated cell survival proteins Bcl-2 and Bcl-X (L), but upregulated apoptotic proteins Bax, Bad, and Bmf. |
1(0,0,0,1) | Details |