| Name | VEGFR 2 |
|---|---|
| Synonyms | CD309; CD309 antigen; FLK 1; FLK1; KDR; Kinase insert domain receptor; Kinase insert domain receptor (A type III receptor tyrosine kinase) variant; Protein tyrosine kinase receptor Flk 1… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19576214 | Budd S, Byfield G, Martiniuk D, Geisen P, Hartnett ME: Reduction in endothelial tip cell filopodia corresponds to reduced intravitreous but not intraretinal vascularization in a model of ROP. Exp Eye Res. 2009 Nov;89(5):718-27. Epub 2009 Jul 1. To determine the effect of a vascular endothelial growth factor receptor 2 kinase (VEGFR2) inhibitor on intravitreous neovascularization (IVNV), endothelial tip cell filopodia, and intraretinal vascularization in a rat model of retinopathy of prematurity (ROP). |
6(0,0,0,6) | Details |
| 20101028 | Shimotake J, Derugin N, Wendland M, Vexler ZS, Ferriero DM: Vascular endothelial growth factor receptor-2 inhibition promotes cell death and limits endothelial cell proliferation in a neonatal rodent model of stroke. Stroke. 2010 Feb;41(2):343-9. |
6(0,0,0,6) | Details |
| 19647313 | Oh EJ, Park K, Choi JS, Joo CK, Hahn SK: Synthesis, characterization, and preliminary assessment of anti-Flt1 peptide-hyaluronate conjugate for the treatment of corneal neovascularization. Biomaterials. 2009 Oct;30(30):6026-34. Epub 2009 Jul 31. The VEGF receptor 2 expression was also reduced after treatment with anti-Flt1 peptide-HA conjugate. |
1(0,0,0,1) | Details |
| 18317697 | Choi SC, Choi JH, Shim WJ, Lim DS: P19 embryonal carcinoma cells: a new model for the study of endothelial cell differentiation. Biotechnol Lett. 2008 Jul;30(7):1169-75. Epub 2008 Mar 4. A prominent capillary-like network including PECAM-1 positive cells and upregulated expression of endothelial markers Tie-1, Tie-2, Flk-1 and PECAM-1 were identified in the DMSO-treated group during EB formation as well as after VEGF treatment. |
1(0,0,0,1) | Details |
| 18413228 | Peterson KJ, Sadowsky JD, Scheef EA, Pal S, Kourentzi KD, Willson RC, Bresnick EH, Sheibani N, Gellman SH: A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor. Anal Biochem. 2008 Jul 1;378(1):8-14. Epub 2008 Mar 28. Vascular endothelial growth factor (VEGF) is a homodimeric proangiogenic protein that induces endothelial cell migration and proliferation primarily through interactions with its major receptors, VEGFR-1 and VEGFR-2. |
1(0,0,0,1) | Details |