| Name | hemoglobin (protein family or complex) |
|---|---|
| Synonyms | Hemoglobin; Hemoglobins |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18681461 | Barshteyn N, Elfarra AA: Detection of multiple globin monoadducts and cross-links after in vitro exposure of rat erythrocytes to S-(1,2-dichlorovinyl)- sulfoxide and after in vivo treatment of rats with S-(1,2-dichlorovinyl)- sulfoxide. Chem Res Toxicol. 2008 Sep;21(9):1716-25. Epub 2008 Aug 6. Collectively, the results indicate at least 4 out of the 5 moieties of the rat hemoglobin heterodimer may be alkylated by DCVCS, in reactions that could also lead to the formation of multiple cross-links. |
2(0,0,0,2) | Details |
| 17718518 | Boys BL, Kuprowski MC, Konermann L: Symmetric behavior of hemoglobin alpha- and beta- subunits during acid-induced denaturation observed by electrospray mass spectrometry. Biochemistry. 2007 Sep 18;46(37):10675-84. Epub 2007 Aug 24. Liquid chromatography and tandem mass spectrometry reveal significant levels of sulfoxide formation for all four residues in commercially obtained metHb. |
2(0,0,0,2) | Details |
| 20216203 | Shainhouse JZ, Grierson LM, Naseer Z: A Long-Term, Open-Label Study to Confirm the Safety of Topical Diclofenac Solution Containing in the Treatment of the Osteoarthritic Knee. Am J Ther. 2010 Mar 5. Individual subject laboratory test shift to abnormal occurred for hemoglobin (3.2%), aspartate aminotransferase (6.4%), alanine aminotransferase (7.3%), and (4.2%), but few shifts (less than 0.3% per variable) were clinically significant. |
1(0,0,0,1) | Details |
| 18032060 | Foresti M, Avallone B: Only complete rejoining of DNA strand breaks after UVC allows K562 cell proliferation and DMSO induction of erythropoiesis. J Photochem Photobiol B. 2008 Jan 30;90(1):8-16. Epub 2007 Oct 23. Conversely, if DMSO was added when the resealing of DNA strand breaks was complete, surviving K562 cells retained full growth capacity, and their progeny underwent erythroid differentiation with normal levels of erythroid proteins, dehydrase and hemoglobin. |
1(0,0,0,1) | Details |