Protein Information

Name adenylyl cyclase
Synonyms ADCY 7; ATP pyrophosphate lyase; Adenylyl cyclase; ADCY7; ADCY7 protein; ATP pyrophosphate lyase 7; Adenylate cyclase 7; Adenylate cyclase type 7…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
19339661 Fricks IP, Carter RL, Lazarowski ER, Harden TK: Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems. J Pharmacol Exp Ther. 2009 Jul;330(1):162-8. Epub 2009 Apr 1.


Inhibition of cAMP formation by nucleotide sugars also was observed in direct assays of adenylyl cyclase activity in membranes prepared from P2Y (14)-C6 cells.
2(0,0,0,2) Details
18596479 Sivasankar M, Nofziger C, Blazer-Yost B: Cyclic adenosine monophosphate regulation of ion transport in porcine vocal fold mucosae. Laryngoscope. 2008 Aug;118(8):1511-7.


The present study examined whether the adenylyl cyclase activator, forskolin, would increase cAMP concentration in porcine vocal fold mucosa and whether the effects of increased cAMP would be manifested as a functional increase in transepithelial ion transport.
2(0,0,0,2) Details
17337170 Li X, Shen F, Zhang Y, Zhu J, Huang L, Shi Q: Functional characterization of cell lines for high-throughput screening of human neuromedin U receptor subtype 2 specific agonists using a luciferase reporter gene assay. Eur J Pharm Biopharm. 2007 Aug;67(1):284-92. Epub 2007 Jan 23.


This assay utilized the signal transduction pathway of hNMU2R, which is positively coupled to adenylyl cyclase and downstream calcium signal pathways.
1(0,0,0,1) Details