Protein Information

Name FRAP
Synonyms FK506 binding protein 12 rapamycin complex associated protein 1; FK506 binding protein 12 rapamycin associated protein 1; FKBP12 rapamycin complex associated protein 1; FKBP12 rapamycin complex associated protein; FRAP; FRAP 1; FRAP 2; FRAP1…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
18292679 Raphael J, Zuo Z, Abedat S, Beeri R, Gozal Y: Isoflurane preconditioning decreases myocardial infarction in rabbits via up-regulation of hypoxia inducible factor 1 that is mediated by mammalian target of rapamycin. Anesthesiology. 2008 Mar;108(3):415-25.

4(0,0,0,4) Details
18258179 Nipper ME, Majd S, Mayer M, Lee JC, Theodorakis EA, Haidekker MA: Characterization of changes in the viscosity of lipid membranes with the molecular rotor FCVJ. Biochim Biophys Acta. 2008 Apr;1778(4):1148-53. Epub 2008 Jan 16.


The most common methods to measure changes in membrane viscosity are fluorescence recovery after photobleaching (FRAP) and fluorescence anisotropy.
3(0,0,0,3) Details
18566692 Andresen M, Regueira T, Bruhn A, Perez D, Strobel P, Dougnac A, Marshall G, Leighton F: Lipoperoxidation and protein oxidative damage exhibit different kinetics during septic shock. Mediators Inflamm. 2008;2008:168652.


At admission, thiobarbituric acid reactive substances (TBARSs), plasma protein carbonyls, plasma protein methionine sulfoxide (MS), ferric/reducing antioxidant power (FRAP), total red blood cell glutathione (RBCG), uric acid (UA), and bilirrubin levels were increased (P < .05).
2(0,0,0,2) Details
18491231 Ozpolat B, Akar U, Zorrilla-Calancha I, Vivas-Mejia P, Acevedo-Alvarez M, Lopez-Berestein G: Death-associated protein 5 (DAP5/p97/NAT1) contributes to retinoic acid-induced granulocytic differentiation and arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. Apoptosis. 2008 Jul;13(7):915-28.


Furthermore, DAP5/p97 expression was upregulated by inhibition of the PI3K/Akt/mammalian target of rapamycin (mTOR) pathway via LY294002 and via rapamycin.
1(0,0,0,1) Details
19035837 Dini I, Tenore GC, Dini A: S-alkenyl cysteine sulfoxide and its antioxidant properties from Allium cepa var. tropeana (red onion) seeds. J Nat Prod. 2008 Dec;71(12):2036-7.

The antioxidant activity of an extract containing cysteine sulfoxides and compound 1 was evaluated using the FRAP and DPPH tests.
1(0,0,0,1) Details