Protein Information

Name glucagon
Synonyms GCG; GLP 1; GLP1; GLP 2; GLP2; GRPP; Glicentin related polypeptide; Glucagon…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
19402179 Ichiba H, Ogawa T, Yajima T, Fukushima T: Analysis of hydroxyl radical-induced oxidation process of glucagon by reversed-phase HPLC and ESI-MS/MS. Biomed Chromatogr. 2009 Oct;23(10):1051-8.

In addition, production of (27) Met sulfoxide enantiomer was confirmed by RP-HPLC analysis. cAMP production in a HepG2 cell induced by (27) Met sulfoxide glucagon was reduced to approximately 75% as compared with that induced by the native form of glucagon.
83(1,1,1,3) Details
18645497 Ito T, Omori K, Rawson J, Todorov I, Asari S, Kuroda A, Shintaku J, Itakura S, Ferreri K, Kandeel F, Mullen Y: Improvement of canine islet yield by donor pancreas infusion with a p38MAPK inhibitor. Transplantation. 2008 Jul 27;86(2):321-9.


Plasma C-peptide levels after glucagon challenge were higher in animals receiving p38IH-treated islets (n=5) versus untreated islets (n=4) (0.40+/-0.78 vs. 0.21+/-0.05 ng/mL, P <0.05).
1(0,0,0,1) Details