Protein Information

Name fatty acid synthase
Synonyms FAS; FAS; FASN; FASN protein; Fatty acid synthase; OA 519; FASN proteins; Fatty acid synthases…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
18555493 Horiguchi A, Asano T, Asano T, Ito K, Sumitomo M, Hayakawa M: Pharmacological inhibitor of fatty acid synthase suppresses growth and invasiveness of renal cancer cells. J Urol. 2008 Aug;180(2):729-36. Epub 2008 Jun 13.

6(0,0,0,6) Details
19033394 Tshala-Katumbay D, Monterroso V, Kayton R, Lasarev M, Sabri M, Spencer P: Probing mechanisms of axonopathy. Toxicol Sci. 2009 Feb;107(2):482-9. Epub 2008 Nov 25.


Analysis of the lumbosacral proteome by 2-dimensional differential in-gel electrophoresis and matrix-assisted laser desorption ionization time-of-flight/tandem mass spectrometry revealed 34 proteins markedly modified by 2,5-HD of which neurofilament triplet L, gelsolin, protein disulfide isomerase, glutathione S-transferase, nicotinamide adenine dinucleotide (reduced) dehydrogenase 1 alpha, pyruvate kinase, and fatty acid synthase were also modified by 1,2-DAB.
1(0,0,0,1) Details