| 6320891 |
Amuro N, Okada S, Goto Y, Shukuya R: Synthesis of cytochrome c oxidase in the liver of Rana catesbeiana tadpole treated with griseofulvin. Biochim Biophys Acta. 1984 Feb 24;781(1-2):14-7.
The effect of griseofulvin treatment on the synthesis of cytochrome c oxidase was studied with the liver of the tadpole, Rana catesbeiana. (1) In the liver of tadpole treated with griseofulvin, a ferrochelatase inhibitor, the synthesis of heme a, but not cytochrome c oxidase protein, is inhibited. (2) The apocytochrome c oxidase which is formed in the liver of tadpole treated with griseofulvin is converted to the active holoenzyme by exogenously added heme a. |
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